coronary artery disease

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository with detailed results at https://github.com/lhncbc/CRI/tree/master/regCTG

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Study Counts

Type	Study_count
Total_Studies	2791
interventional	1862
Observational	777
Registry	152

Studies over Time

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Device	443
Drug	431
Procedure	203
Other	181
Drug|placebo	171
Behavioral	146
Diagnostic Test	28
Device|Drug	24
Device|Procedure	22
Dietary Supplement|placebo	19
Dietary Supplement	18
Biological	15
Device|Other	14
Drug|Procedure	14
Drug|Other	13
Behavioral|Other	12
Radiation	12
Other|Procedure	11
Biological|placebo	10
Behavioral|Drug	6
Drug|Other|placebo	6
Behavioral|Procedure	4
Combination Product	4
Genetic	4
Other|placebo	3
Behavioral|Device	2
Behavioral|Drug|Other	2
Behavioral|Drug|Procedure	2
Biological|Other	2
Device|Drug|placebo	2
Device|Drug|Procedure	2
Device|placebo	2
Diagnostic Test|Other	2
Dietary Supplement|Drug	2
Drug|placebo|Procedure	2
placebo|Procedure	2
Procedure|Radiation	2
Behavioral|Biological|Drug	1
Behavioral|Dietary Supplement|Other	1
Behavioral|Drug|placebo	1
Behavioral|Genetic	1
Behavioral|Genetic|Other	1
Biological|Device|Other	1
Biological|Device|placebo	1
Biological|Other|placebo	1
Combination Product|Device	1
Combination Product|Drug|placebo	1
Device|Other|Procedure	1
Diagnostic Test|Genetic	1
Diagnostic Test|Procedure	1
Dietary Supplement|Drug|Other	1
Dietary Supplement|Drug|Other|Procedure	1
Dietary Supplement|Drug|placebo	1
Dietary Supplement|Other	1
Drug|Genetic	1
Drug|Genetic|Other	1
Drug|placebo|Radiation	1
Drug|Procedure|Radiation	1
Genetic|placebo	1
Other|Radiation	1
placebo	1

Count of Studies by Intervention (normalized and mapped)

Intervention_type	intervention	Study_count	Date of First Study
placebo	placebo	169	2014
Drug	clopidogrel	88	2010
Drug	aspirin	54	2014
Drug	ticagrelor	46	2014
Drug	atorvastatin	28	2014
Procedure	percutaneous coronary intervention	27	2014
Drug	prasugrel	27	2011
Drug	ezetimibe	22	2014
Other	standard care	21	2017
Drug	regadenoson	18	2009
Drug	rosuvastatin	14	2009
Behavioral	exercise training	13	2010
Drug	saline	12	2013
Other	exercise	11	2018
Procedure	pci	11	2014
Drug	simvastatin	10	2018
Drug	adenosine	9	2010
Drug	heparin	9	2018
Drug	metformin	9	2016
Device	bare metal stent	8	2009
Procedure	cabg	8	2010
Other	control	8	2010
Device	drug-eluting stent	8	2017
Device	drug eluting stent	8	2009
Drug	propofol	8	2019
Device	xience	8	2017
Procedure	coronary angiography	7	2017
Drug	ranolazine	7	2015
Drug	abt-335	6	2008
Device	coronary stent	6	2010
Device	cypher	6	2009
Drug	ivabradine	6	2017
Drug	niacin	6	2013
Procedure	percutaneous coronary intervention (pci)	6	2014
Procedure	remote ischemic preconditioning	6	2010
Drug	cilostazol	5	2014
Drug	colchicine	5	2020
Device	everolimus-eluting stent	5	2010
Device	ffr	5	2010
Device	ivus	5	2014
Device	orsiro	5	2015
Drug	pioglitazone	5	2009
Drug	sevoflurane	5	2019
Device	sirolimus-eluting stent	5	2013
Device	stent	5	2011
Procedure	stenting	5	2013
Drug	bivalirudin	4	2013
Drug	cangrelor	4	2013
placebo	comparator: ezetimibe, placebo	4	2004
Procedure	coronary artery bypass grafting	4	2018
Device	coronary artery stenting	4	2017
Device	cypher select	4	2010
Device	cypher sirolimus-eluting stent	4	2007
Drug	dalcetrapib	4	2011
Behavioral	diet, fat-restricted	4	1999
Device	drug eluting balloon	4	2009
Biological	evolocumab	4	2017
Procedure	forearm vascular study	4	2009
Other	intervention	4	2018
Drug	mk0653, ezetimibe	4	2004
Device	paclitaxel-eluting stent	4	2013
Drug	pb127 for injectable suspension	4	2008
Drug	remifentanil	4	2019
Device	resolute integrity stent	4	2012
Drug	rvx000222	4	2011
Drug	sitagliptin	4	2014
Behavioral	smoking cessation	4	2007
Drug	statin	4	2019
Drug	thienopyridine	4	2011
Drug	ticagrelor 180mg	4	2014
Drug	ticagrelor 90mg	4	2014
Drug	valsartan	4	2009
Drug	xenon	4	2010
Device	xience vâ® everolimus eluting coronary stent	4	2006
Device	absorb bvs	3	2014
Drug	acarbose	3	2009
Drug	acetylsalicylic acid	3	2013
Other	aerobic exercise training	3	2012
Drug	amlodipine	3	2010
Device	angiography	3	2018
Drug	aspirin monotherapy	3	2010
Drug	aspirin,clopidogrel	3	2010
Drug	ateronon	3	2009
Device	bare-metal stent	3	2010
Procedure	blood sample	3	2007
Behavioral	cardiac rehabilitation	3	2009
Drug	celecoxib	3	2007
Biological	cells	3	2018
Dietary Supplement	coenzyme q10	3	2010
Dietary Supplement	control diet	3	2014
Procedure	coronary artery bypass graft surgery	3	2011
Device	coronary intervention	3	2013
Procedure	coronary stenting	3	2017
Device	ct-scan	3	2018
Device	cypher sirolimus-eluting coronary stent	3	2005
Device	cypher stent	3	2010
Drug	dabigatran	3	2013
Drug	dalcetrapib (ro4607381)	3	2008
Drug	dipyridamole	3	2011
Device	drug eluting coronary stent	3	2006
Other	education	3	2012
Device	endeavor	3	2008
Drug	fenofibrate	3	2016
Behavioral	health coaching	3	2013
Drug	hormone replacement therapy	3	1999
Biological	influenza vaccine	3	2008
Procedure	invasive coronary angiography	3	2020
Behavioral	lifestyle	3	2011
Behavioral	lifestyle intervention	3	2019
Drug	nitric oxide	3	2018
Drug	nitroglycerin	3	2016
Drug	ono-1101	3	2009
Other	optimal medical therapy	3	2018
Drug	oxygen	3	2014
Device	promus element	3	2010
Device	promus element coronary stent system	3	2011
Device	resolute onyxâ„¢ zotarolimus-eluting coronary stent system	3	2018
Drug	rosuvastatin calcium	3	2006
Device	sirolimus eluting stent	3	2010
Drug	sufentanil	3	2014
Device	synergy stent	3	2016
Device	taxus libertã©-sr	3	2006
Device	taxusâ„¢ express2â„¢ paclitaxel eluting coronary stent	3	2006
Drug	tirofiban	3	2011
Drug	tranexamic acid	3	2012
Drug	vericiguat (bay1021189)	3	2018
Drug	vitamin c	3	1999
Drug	vitamin e	3	1999
Device	xience v	3	2009
Behavioral	NA	2	2014
Drug	1	2	2011
Drug	12-month dapt	2	2018
Drug	a-002	2	2007
Drug	abciximab	2	2005
Biological	adalimumab	2	2009
Behavioral	aerobic training	2	2016
Dietary Supplement	aged garlic extract	2	2019
Procedure	ai-700 contrast-enhanced echocardiography	2	2005
Drug	alirocumab	2	2018
Drug	aliskiren	2	2009
Dietary Supplement	almonds	2	2008
Device	amm fortitude bioresorbable drug-eluting coronary scaffold	2	2014
Device	amplatzer vascular plug	2	2019
Device	angiography guided pci	2	2016
Device	angiography guided percutaneous coronary angioplasty with promus element stent implantation	2	2013
Device	angioshield	2	2015
Drug	apl180	2	2009
Drug	aspirin, clopidogrel	2	2007
Drug	atorvastatin (lipitor)	2	2007
Drug	atorvastatin 10 mg	2	2007
Drug	atorvastatin 20 mg	2	2007
Drug	atorvastatin calcium	2	2007
Drug	azd5718 oral suspension	2	2016
Behavioral	beating the blues (btb)	2	2015
Drug	berberine	2	2017
Drug	binodenoson	2	2009
Drug	bradykinin receptor antagonist (hoe-140)	2	2009
Device	buma supreme	2	2016
Drug	caffeine	2	2007
Drug	candesartan	2	2008
Procedure	cardiac catheterization	2	2011
Device	cardiac mri	2	2014
Drug	closone	2	2013
Drug	colestipol	2	1999
Drug	contrast	2	2018
Procedure	conventional cabg	2	2018
Procedure	coronary angioplasty	2	2016
Procedure	coronary angioplasty with stent implantation	2	2014
Procedure	coronary computed tomography angiography	2	2008
Device	coronary ct angiography	2	2011
Other	coronary cta	2	2011
Device	coronary pci guided by angiography	2	2018
Device	coronary pci guided by oct	2	2018
Device	coronary stent implantation	2	2006
Behavioral	counseling	2	2019
Combination Product	cswt	2	2017
Diagnostic Test	ct angiography	2	2020
Other	ct coronary angiography	2	2011
Procedure	cto coronary angioplasty	2	2016
Drug	custodiol	2	2014
Drug	custodiol-n	2	2014
Drug	dapagliflozin	2	2016
Behavioral	decision aid	2	2012
Drug	dexmedetomidine	2	2019
Other	diagnostic cardiac imaging	2	2012
Behavioral	diet	2	2014
Procedure	endoscopic radial artery harvest	2	2013
Drug	enoxaparin	2	2014
Drug	escitalopram	2	2007
Drug	estrogen replacement therapy	2	1999
Drug	estrogens	2	1999
Drug	etomidate	2	2011
Device	everolimus eluting stent	2	2010
Drug	ezetimibe 10 mg	2	2007
Drug	fentanyl	2	2016
Diagnostic Test	ffrct	2	2017
Drug	fixed dose combination of clopidogrel	2	2010
Drug	fixed dose combination of clopidogrel/aspirin	2	2010
Drug	folic acid	2	1999
Device	fractional flow reserve (ffr)	2	2016
Behavioral	health education	2	2018
Other	high-intensity interval training	2	2011
Device	hybrid coronary revascularization	2	2017
Procedure	hybrid revascularization	2	2014
Device	icd implantation	2	2009
Device	ifr	2	2013
Biological	implantation	2	2012
Drug	intensive insulin treatment	2	2014
Behavioral	interactive education	2	2006
Other	interval exercise training	2	2014
Other	interval training	2	2012
Procedure	intravascular ultrasound	2	2008
Drug	iobitridol	2	2010
Drug	ketamine	2	2019
Drug	laropiprant	2	2010
Behavioral	lifestyle counseling	2	2013
Drug	liraglutide	2	2014
Device	lithotripsy	2	2018
Drug	lovastatin	2	2005
Drug	lumason	2	2015
Other	manual compression	2	2011
Drug	medication	2	2011
Biological	mesendo	2	2008
Drug	methotrexate	2	2008
Drug	methylprednisolone	2	2005
Dietary Supplement	milk fat	2	2011
Drug	mipomersen sodium	2	2008
Procedure	mitral valve annuloplasty	2	2018
Behavioral	moderate intensity continuous exercise training	2	2016
Drug	moxifloxacin	2	2018
Drug	n-acetyl cysteine	2	2013
Drug	n-acetylcysteine	2	2011
Device	neovas bcs	2	2014
Device	neuromuscular electrical stimulation	2	2018
Drug	nicorandil	2	2011
Device	nirs	2	2013
Drug	nitrous oxide	2	2007
Procedure	no-touch vein harvesting technique	2	2017
Other	no intervention	2	2017
Procedure	no touch technique	2	2018
Behavioral	nudge	2	2019
Device	oct guided pci	2	2017
Device	ofdi	2	2013
Device	omt	2	2010
Device	orbusneich combo stentâ„¢	2	2015
Drug	p2y12 antagonist	2	2012
Drug	p2y12 inhibitor	2	2017
Behavioral	peer support	2	2006
Device	percutaneous coronary intervention (pci) with paclitaxel-eluting stent (taxus element) implantation	2	2007
Device	pet	2	2016
Procedure	pharmacologic case management	2	2006
Other	physiotherapy	2	2019
Drug	pitavastatin	2	2009
placebo	placebo for influenza vaccine	2	2008
placebo	placebo rvx000222	2	2011
Dietary Supplement	plant sterols	2	2014
Drug	plavix with astrix	2	2013
Drug	prasugrel 10 mg	2	2010
Drug	prasugrel 5mg	2	2017
Drug	prasugrel 60 mg	2	2014
Drug	pravastatin	2	2016
Behavioral	pre	2	2016
Drug	progesterone	2	2012
Drug	pz-128	2	2015
Device	rapamycin	2	2008
Biological	red blood cell transfusion	2	2016
Other	remote ischemic pre-conditioning	2	2014
Device	resolute integrity	2	2012
Device	resolute integrityâ„¢ zotarolimus-eluting coronary stent system	2	2018
Drug	rivaroxaban	2	2013
Drug	rocuronium	2	2019
Drug	rosuvastatin calcium10mg	2	2009
Device	rotational atherectomy	2	2015
Drug	rubidium-82	2	2011
Other	same day discharge	2	2013
Drug	sarpogrelate	2	2014
Device	selective vagus nerve stimulation	2	2009
Other	sham control	2	2016
Other	sham procedure	2	2014
Drug	simvastatin 20 mg	2	2007
Drug	simvastatin 40 mg	2	2007
Other	single photon emission computed tomography	2	2011
Device	sirolimus-coated bx velocity stent	2	2005
Other	spect	2	2014
Other	standard cpb	2	2018
Drug	standard medical therapy	2	2016
Behavioral	standard risk assessment	2	2013
Procedure	stress-mri	2	2016
Diagnostic Test	stress cardiac mri	2	2019
Procedure	stress echocardiography	2	2015
Drug	sugar pill	2	2012
Device	synergy	2	2012
Device	taxus stent	2	2008
Device	taxusâ„¢ express	2	2006
Behavioral	text messaging	2	2016
Drug	ticagrelor maintenance dose	2	2014
Diagnostic Test	tomography angiography	2	2017
Behavioral	training	2	2007
Behavioral	transcendental meditation	2	2015
Procedure	transit-time flowmetry	2	2008
Procedure	ultrasound guidance	2	2012
Other	ultrasound of aorta	2	2013
Device	uncoated bx velocity balloon-expandable stent	2	2007
Drug	vildagliptin	2	2017
Device	virtual therapeutic support	2	2019
Drug	vitamin b12	2	1999
Drug	warfarin	2	2018
Device	xience primeâ„¢	2	2010
Device	xience v eecss	2	2010
Device	xience vâ®	2	2010
Device	xience vâ®/ xience primeâ„¢	2	2010
Device	zomaxxâ„¢ drug-eluting coronary stent system	2	2005
Device	zotarolimus-eluting stent	2	2010
Device	zotarolimus eluting stent	2	2010
Procedure	‘spy’ nirf during cabg	1	2014
Procedure	- percutaneous coronary intervention	1	2019
Behavioral	“care4heart” programme	1	2018
Drug	) ezetimibe	1	2007
Drug	) simvastatin	1	2005
Other	[11c]‑dmdpa	1	2016
Drug	[3h] bms747158	1	2009
Drug	0.5	1	2012
Drug	0.9% nacl	1	2012
Drug	1-month dapt	1	2015
Drug	1-months dapt	1	2018
Drug	1 month dapt	1	2017
Device	1 stent	1	2015
Other	1 week uv dosimeter	1	2013
Dietary Supplement	1% milk	1	2009
Drug	1.5 ml subcutaneous solution	1	2019
Drug	1/10 na/ee	1	2008
Radiation	1/2 dose of 99mtc/201tl tracers	1	2011
Drug	10 na	1	2008
Drug	12-month dual anti-platelet therapy	1	2017
Behavioral	12-week risk reduction program, managed by a heart health educator	1	2007
Other	12 months dual anti-platelet therapy	1	2017
Drug	123i-cmice-013	1	2012
Device	17beta estradiolvalerat-eluting stent	1	2006
Drug	18f-fluorodeoxyglucose	1	2013
Other	18f-naf pet	1	2015
Other	18f-naf pet/coronary cta imaging	1	2015
Radiation	2 dose of 99mtc	1	2011
Device	2 stents	1	2015
Drug	20 mg	1	2007
Radiation	201tl tracers	1	2011
Drug	240 mg iodine	1	2014
Procedure	3-dimensional coronary angiography	1	2007
Other	3 months dual anti-platelet therapy	1	2017
Drug	3 months of dual antiplatelet therapy (dapt)	1	2015
Drug	300 mg iodine	1	2014
Dietary Supplement	30g	1	2018
Procedure	320 volume detector computed tomography	1	2009
Drug	370 mg iodine	1	2014
Device	38 mm)	1	2017
Other	3t cmr	1	2012
Other	4-day food diary	1	2013
Device	4.0 cypher sirolimus-eluting coronary stent	1	2005
Device	4r cardiac catheters	1	2017
Drug	6-month dual anti-platelet therapy	1	2017
Drug	6 months dapt	1	2017
Drug	6% hydroxy ethyl starch	1	2012
Drug	6% hydroxyethyl starch 200	1	2012
Device	64 channel vct	1	2006
Other	68ga-nodaga-rgd pet	1	2018
Other	68ga-nodaga-rgd pet/ct	1	2018
Device	6f sheath	1	2017
Device	6f sheath/guide catheter combination	1	2017
Drug	7.2% nacl	1	2012
Drug	7.2% nacl/6% hydroxyethyl starch 200/0.5	1	2012
Device	70% of sirolimus dose	1	2005
Device	7f ensure medical vascular closure device	1	2007
Device	7f sheathless guide catheter	1	2017
Diagnostic Test	82-rb pet	1	2018
Diagnostic Test	82-rb pet/ct as part of standard care, not a comparator	1	2018
Diagnostic Test	99mtc-sestamibi	1	2013
Drug	99mtechnicium (sestamibi	1	2011
Drug	99mtechnicium (sestamibi/tetrofosmin)	1	2011
Genetic	9p21	1	2012
Other	a-view	1	2011
Procedure	a new non-invasive imaging technique	1	2012
Behavioral	a nurse led home-based education	1	2005
Behavioral	a nurse led home-based education/support programme	1	2005
Procedure	aa	1	2007
Device	abbott vascular absorb everolimus eluting bioresorbable vascular scaffold system	1	2011
Device	abbott vascular xience everolimus eluting coronary stent system	1	2011
Device	abbott xience family everolimus-eluting stent	1	2015
Device	abbott xience v	1	2008
Device	absorb	1	2016
Device	absorb bvs system	1	2013
Device	absorb bvsâ„¢	1	2013
Device	absorb gt1 bvs	1	2017
Device	absorbâ„¢ bvs	1	2013
Drug	abt-335/atorvastatin calcium	1	2006
Drug	abt-335/rosuvastatin calcium	1	2006
Drug	abt-335/simvastatin	1	2006
Drug	ace	1	2014
Drug	ace-i (lisinopril)	1	2018
Drug	ace-i (lisinopril)/arb (losartan)	1	2018
Drug	ace/arb continuation	1	2014
Drug	ace/arb withdrawal	1	2014
Drug	acetated ringer`s solution	1	2011
Drug	acetylcholine	1	2018
Drug	acetylsalicyclic acid (asa)	1	2006
Drug	acetylsalicylic acid 75mg tablet	1	2016
Drug	acp-501	1	2012
Procedure	acr-pci	1	2018
Drug	act-246475	1	2017
Other	action plans	1	2009
Radiation	active comparator: invasive coronary angiography (ica)	1	2013
Behavioral	active comparator: traditional expressive writing	1	2010
Procedure	acute normovolemic hemodilution	1	2017
Drug	adenosine infusion at 200î¼g	1	2015
Drug	adenosine infusion at 200î¼g/kg/min	1	2015
Other	adenosine stress dual-source ctp	1	2009
Drug	adjustment of clopidogrel dose	1	2006
Device	adrcs processed by the celution system	1	2012
Biological	adult stem cells	1	2009
Other	advanced cardiac imaging	1	2010
Device	advanced monitoring	1	2008
Biological	advegfxc1	1	2019
Behavioral	advice in exercise training (	1	2011
Behavioral	advice in exercise training (/ex)	1	2011
Behavioral	advice on what food to choose	1	2016
Behavioral	advice on what food to choose/eat	1	2016
Other	aerobic	1	2013
Other	aerobic exercises	1	2019
Behavioral	aerobic interval training	1	2010
Other	aerobic training (aero)	1	2017
Other	aerobic/strength training	1	2013
Dietary Supplement	aged garlic extract (age)	1	2019
Dietary Supplement	aged garlic extract/coenzyme q10	1	2009
Device	agent paclitaxel-coated balloon	1	2014
Drug	aggressive lipid therapy	1	2012
Procedure	aggressive strategy	1	2008
Drug	ai-700	1	2008
Other	ait group	1	2016
Drug	aleglitazar	1	2012
Drug	alirocumab 75 mg	1	2018
Drug	alirocumab 75 mg/ml [praluent]/ rosuvastatin 10mg/daily	1	2018
Drug	alirocumab sar236553	1	2016
Drug	allopurinol	1	2013
Drug	alpha-lipoic acid	1	2013
Drug	alt-2074	1	2007
Other	alternate day fasting	1	2009
Other	altitude simulation	1	2014
Other	ambient air	1	2017
Behavioral	ambio health remote monitoring	1	2017
Procedure	ambulation orderly	1	2015
Drug	amiloride	1	2010
Dietary Supplement	amino acids	1	2015
Device	amm aptitude bioresorbable drug-eluting coronary scaffold	1	2015
Device	amm magnitude bioresorbable drug-eluting coronary scaffold	1	2016
Device	amplatzer vascular plug 4	1	2018
Drug	anacetrapib	1	2008
Drug	anagliptin	1	2014
Drug	anakinra	1	2012
Procedure	anchoring technique	1	2017
Drug	androgel 5 grams	1	2006
Procedure	anesthesia for coronary artery surgery	1	2005
Drug	anfibatide	1	2012
Procedure	angio-guided cabg	1	2018
Procedure	angio-guided pci	1	2005
Device	angio-guided pci with ees	1	2012
Device	angio-guided pci with ees/bes	1	2012
Procedure	angio-guided surgical revascularization	1	2014
Procedure	angio-pci	1	2018
Procedure	angio guided cabg	1	2020
Procedure	angiographic guided pci	1	2017
Procedure	angiography-derived ffr	1	2020
Procedure	angiography-guided cabg	1	2015
Device	angiography-guided paclitaxel drug-coated balloon angioplasty	1	2020
Device	angiography-guided pci	1	2018
Device	angiography-guided pci with bioresorbable vascular scaffold	1	2015
Device	angiography guidance	1	2020
Device	angiography guided percutaneous coronary angioplasty with resolute integrity stent insertion	1	2013
Device	angiography/optical coherence tomography evaluations	1	2017
Device	angioguard distal protection device	1	2005
Device	angiolite	1	2017
Device	angiolite stent	1	2016
Procedure	angioplasty	1	2019
Device	angiosculpt scoring balloon catheter	1	2008
Device	angiosculptâ® scoring balloon catheter	1	2008
Procedure	antegrade wire escalation strategy	1	2015
Dietary Supplement	anthocyanins	1	2018
Drug	anti-ischemic drug therapy	1	2006
Drug	anticoagulants	1	2016
Drug	antidepressant medications	1	2015
Device	antigravity treadmill (alter-g)	1	2015
Drug	antiplatelet therapy	1	2019
Drug	antiplatelets	1	2016
Device	any abiomed impellaâ® device approved for use in high-risk pci	1	2015
Other	aorta	1	2012
Procedure	aortic no-touch opcabg	1	2017
Procedure	aortoradial graft (free ra)	1	2013
Device	app support programme (asp) group	1	2019
Drug	aprotinin	1	2005
Procedure	aprotinine	1	2005
Drug	arb (losartan)	1	2018
Drug	arb continuation	1	2014
Drug	arb withdrawal	1	2014
Drug	argatroban	1	2007
Device	art18z bioresorbable stent	1	2013
Other	arterial doppler for screening asymptomatic	1	2007
Other	arterial doppler for screening asymptomatic/significant extracoronary arterial stenoses in all arterial beds	1	2007
Device	artimes pro low profile dilatation catheter	1	2017
Drug	aspirin / clopidogrel	1	2017
Drug	aspirin / placebo	1	2009
Drug	aspirin / plavix (clopidogrel bisulfate)	1	2009
Drug	aspirin / pregrel (clopidogrel resinate)	1	2009
Drug	aspirin / ticagrelor	1	2015
Drug	aspirin 100 mg	1	2015
Drug	aspirin continuation	1	2014
Drug	aspirin discontinuation	1	2014
Drug	aspirin enteric-coated tablets	1	2012
Drug	aspirin loading dose	1	2014
Drug	aspirin maintenance dose	1	2014
Drug	aspirin tablets	1	2007
Drug	aspirin, betaloc, atorvastatin, rosuvastatin, clopidogrel, ticagrelor	1	2017
Drug	aspirin, prasugrel	1	2009
Drug	aspirin/clopidogrel	1	2009
Drug	aspirin/clopidogrel / prasugrel	1	2009
Drug	aspirin/p2y12 antagonist	1	2014
Drug	aspirin/thienopyridine	1	2011
Drug	atenolol	1	2005
Drug	atenolol/hctz/trandolapril	1	2005
Drug	atorvastatin-esomeprazole	1	2009
Drug	atorvastatin-omeprazole	1	2009
Drug	atorvastatin-pantoprazole	1	2009
Drug	atorvastatin-ranitidine	1	2009
Drug	atorvastatin (drug)	1	2006
Drug	atorvastatin 10mg versus 40mg.	1	2010
Drug	atorvastatin 20 mg / pioglitazone 30 mg	1	2011
Drug	atorvastatin 20mg	1	2011
Drug	atorvastatin 40 mg	1	2007
placebo	atorvastatin vs placebo	1	2009
Drug	atorvastatin, high vs low dose	1	2009
Drug	atorvastatin, lipitor	1	2006
Drug	atorvastatin,pravastatin	1	2006
Drug	atorvastatin; fenofibrate; niacin	1	2007
Behavioral	attention comparison	1	2012
Behavioral	attention control	1	2019
Procedure	audience response system	1	2014
Biological	auto-cd34	1	2012
Biological	auto-cd34/ cells	1	2012
Procedure	autologous bone marrow derived stem cells myocardial transplantation	1	2008
Drug	autologous cd34	1	2018
Drug	autologous cd34/ cells	1	2018
Other	autologous stem cells	1	2008
Device	aviâ® arsenic trioxide drug eluting stent	1	2014
Device	aviâ® arsenic trioxide drug eluting stent delivery system	1	2014
Other	ayurveda	1	2014
Drug	azd5718	1	2017
Drug	azd5718 film-coated tablet, reference treatment	1	2019
Drug	azd5718 ir tablet	1	2016
Drug	azd5718 tablet, formulation a	1	2019
Drug	azd5718 tablet, formulation b	1	2019
Drug	azd5718 tablet, formulation c	1	2019
Drug	azd5718 tablet, formulation d	1	2019
Drug	azd6140	1	2008
Drug	azithromycin capsule	1	2018
Drug	b-blockers	1	2018
Drug	b6	1	2008
Dietary Supplement	b6 vitamin	1	2018
Other	background care	1	2012
Device	balloon	1	2017
Procedure	balloon-stent kissing technique	1	2018
Device	balloon angioplasty	1	2006
Device	bare metal bx velocityâ„¢	1	2005
Device	bare metal coronary stent	1	2006
Device	bd-des (biodegradable polymer drug-eluting stent)	1	2014
Other	bed rotation group	1	2015
Behavioral	behavioral	1	2006
Behavioral	behavioral counseling	1	2006
Behavioral	behavioral counseling/peer support	1	2006
Behavioral	behavioral intervention	1	2012
Behavioral	behavioral interventional program	1	2009
Behavioral	behavioral modification	1	2018
Behavioral	behavioral program a	1	2008
Behavioral	behavioral program b	1	2008
Device	bes	1	2012
Other	best available therapy	1	2013
Drug	beta-carotene	1	1999
Drug	beta blocker	1	2018
Drug	betablocker, diuretics, acei, arb,	1	2007
Drug	bezafibrate	1	2016
placebo	bfgf:placebo plasmid	1	2008
Drug	bfpet	1	2008
Drug	biap	1	2009
Device	bioabsorbable everolimus eluting coronary stent	1	2009
Device	biodegradable-polymer stent	1	2016
Device	biodegradable polymer-des	1	2010
Device	biodegradable polymer limus-eluting stents	1	2010
Device	biodegradable polymer rapamycin-eluting stent	1	2008
Device	biofreedom	1	2015
Device	biofreedom with 1 month dapt	1	2015
Device	biofreedomâ„¢ cocr biolimus a9â„¢ stent	1	2017
Device	biofreedomâ„¢ ss biolimus a9â„¢ stent	1	2017
Device	biolimus-eluting stent	1	2011
Device	biolimus a9-eluting stent	1	2010
Device	biolimus eluting bioresorbable polymer stent	1	2014
Device	biolimus eluting stent	1	2017
Device	biolinx polymer-based zotarolimus-eluting stents	1	2017
Other	biological measurements	1	2011
Device	biomatrix	1	2015
Drug	biomatrix drug eluting stent	1	2014
Device	biomatrix flex stent	1	2012
Device	biomatrix neoflex coronary stent	1	2014
Device	biomatrix stent	1	2012
Device	biomatrix/ultimaster with 6 to 12 months dapt	1	2015
Procedure	biopsy	1	2013
Device	bioresorbable vascular scaffolds (bvs)	1	2017
Device	biosensors biofreedom ba9 drug coated coronary stent	1	2017
Drug	bisoprolol	1	2006
Drug	bisoprolol fumarate 2.5 mg oral tablet	1	2016
Drug	bivalirudin use during epci	1	2019
Procedure	blood sampling - genotyping	1	2007
Procedure	blood sampling - platelet aggregation	1	2007
Other	blood sampling from the coronary sinus	1	2012
Other	blood sampling from the coronary sinus/aorta	1	2012
Diagnostic Test	blood test	1	2019
Combination Product	bmmscs	1	2017
Device	bodymedia	1	2011
Drug	bone marrow derived autologous cd133	1	2016
Drug	bone marrow derived autologous cd133/ selected cell product	1	2016
Other	bone marrow mononuclear cells	1	2011
Device	boston scientific fully absorbable scaffold	1	2015
Procedure	brachial artery reactivity study	1	2003
Dietary Supplement	brazilian cardioprotective diet	1	2018
Dietary Supplement	brazilian cardioprotective diet/30g/day of mixed nuts	1	2018
Device	breathhold spect-mpi	1	2015
Device	bridgepoint medical system (crossboss catheter, stingray catheter, entera guidewire)	1	2008
Device	bs-des (biostable polymer drug-eluting stent)	1	2014
Device	buma	1	2013
Device	buma stent	1	2012
Device	buma supreme des	1	2017
Device	bumaâ„¢	1	2016
Drug	bupivacaine group	1	2018
Drug	bupivacaine hydrochloride	1	2017
Behavioral	burst physical activity	1	2017
Device	bvs	1	2016
Device	bvs absorb scaffold	1	2016
Device	bvs/omt	1	2016
Device	bx cypher stent	1	2005
Device	bx sonic bare metal stent	1	2007
Device	bx velocity stent containing 45%	1	2005
Device	bx velocity stent containing 45%/70% of sirolimus dose	1	2005
Device	c-cathezâ® catheter	1	2017
Procedure	cabg / mitral valve annuloplasty	1	2006
Device	cabg/savr	1	2018
Other	cacs	1	2013
Other	cad	1	2018
Behavioral	cad education	1	2014
Device	cadscorâ®system	1	2019
Other	cag-guided strategy	1	2019
Drug	calcium channel blockers (amlodipine, azelnidipine)	1	2006
Dietary Supplement	calorie-restricted diet	1	2018
Other	calorie restriction	1	2009
Procedure	cardiac computed tomographic angiography (ccta)	1	2011
Device	cardiac computer tomography	1	2011
Procedure	cardiac ct	1	2013
Diagnostic Test	cardiac ct angiogram	1	2018
Device	cardiac ct scan	1	2014
Behavioral	cardiac education class	1	2005
Other	cardiac educational program	1	2019
Device	cardiac gsi	1	2013
Diagnostic Test	cardiac magnetic resonance	1	2017
Other	cardiac magnetic resonance (cmr) imaging techniques	1	2016
Drug	cardiac mri taken using contrast agent, dotaremâ® (gd-dota)	1	2017
Drug	cardiac mri with contrast agent, gadovist	1	2017
Drug	cardiac pet scan w	1	2013
Drug	cardiac pet scan w/18f-fluorodeoxyglucose/rubidium-82	1	2013
Other	cardiac rehabilitation clinic	1	2014
Behavioral	cardiac rehabilitation peer mentorship	1	2014
Device	cardiac shock wave therapy	1	2017
Device	cardiac shock wave therapy(cswt)	1	2012
Procedure	cardiac spect imaging rest	1	2005
Procedure	cardiac spect imaging rest/stress	1	2005
Device	cardiac stabilizer instead of cardiopulmonary bypass	1	2005
Procedure	cardiac surgery	1	2009
Procedure	cardiac surgery scheduled in the afternoon	1	2016
Procedure	cardiac surgery scheduled in the morning	1	2016
Behavioral	cardiofit	1	2005
Device	cardiogoniometry (cgm)	1	2016
Drug	cardiopet	1	2006
Drug	cardiopetâ„¢	1	2013
Diagnostic Test	cardiopulmonary exercise testing	1	2017
Other	cardiovascular magnetic resonance imaging	1	2012
Procedure	cardiovascular measurement	1	2016
Procedure	cardiovascular rehabilitation program using kinect of xbox	1	2016
Procedure	cardiovascular rehabilitation program using paper manual	1	2016
Other	carotid ultrasound	1	2008
Drug	carvedilol	1	2008
Behavioral	case managed home program	1	2018
Procedure	catheterization	1	2009
Device	catheterization, stent deployment	1	2009
Behavioral	cbcr	1	2018
Behavioral	cbt hostility reduction program	1	2006
Procedure	ccta (coronary computed tomography angiography)	1	2012
Radiation	ccta ~ breast shields	1	2015
Diagnostic Test	ccta with selective ffrct	1	2018
Procedure	cell therapy	1	2012
Genetic	cell therapy - autologous cd34 positive cells	1	2004
Device	celt acd	1	2012
Device	celution system	1	2014
Behavioral	center-based cardiac rehabilitation	1	2014
Procedure	centrifugation	1	2011
Device	cep magna mitral pericardial bioprostheses	1	2009
Other	cgms	1	2013
Drug	cgt003 (e2f duplex decoy)	1	2002
Behavioral	change	1	2014
Other	change in the timing of components of usual care	1	2018
Behavioral	change/	1	2014
Drug	chewable aspirin	1	2008
Drug	chixiangshen tongxin granules	1	2011
Other	choice of hospital	1	2018
Other	choice of hospital/home-based cr / movn application	1	2018
Other	choice of hospital/home-based cr / movn application / nudge	1	2018
Behavioral	cholesterol lowering diet	1	2008
Behavioral	choral singing	1	2017
Procedure	chronic total occlusion percutaneous coronary intervention	1	2016
Procedure	chronic total occlusion revascularization	1	2019
Device	chrono carbostent carbofilmâ„¢ coated coronary stent	1	2009
Other	cigarettes	1	2015
Drug	cilostazol 100mg	1	2013
Drug	cilostazol 100mg bid	1	2009
Drug	cilostazol 100mg bid/clopidogrel 150-mg daily	1	2009
Device	cilostazol eluting stent system (ces-1)	1	2017
Drug	cilostazol in addition to aspirin	1	2006
Drug	cilostazol in addition to aspirin/clopidogrel	1	2006
Device	cilotax stent	1	2012
Drug	cipher prescription 1	1	2009
Drug	cipher prescription 2	1	2009
Drug	clarithromycin	1	2005
Biological	clbs16	1	2018
Other	clearsight measurement	1	2016
Behavioral	climb intervention	1	2018
Procedure	clinical follow-up	1	2010
Drug	clopidogrel (over encapsulated) capsule	1	2007
Drug	clopidogrel / aspirin	1	2013
Drug	clopidogrel / aspirin/prasugrel / aspirin	1	2010
Drug	clopidogrel 150-mg daily	1	2009
Drug	clopidogrel 150mg	1	2013
Drug	clopidogrel 600 mg	1	2014
Drug	clopidogrel 75 mg	1	2015
Drug	clopidogrel 75 mg daily	1	2005
Drug	clopidogrel active metabolite	1	2018
Drug	clopidogrel after everolimus-eluting stent implantation	1	2007
Drug	clopidogrel after paclitaxel-eluting stent implantation	1	2007
Drug	clopidogrel after zotarolimus-eluting stent implantation	1	2007
Drug	clopidogrel bisulfate	1	2012
Drug	clopidogrel bisulfate / aspirin	1	2012
Drug	clopidogrel mono-therapy	1	2019
Drug	clopidogrel monotherapy	1	2017
Drug	clopidogrel napadisilate	1	2012
Drug	clopidogrel napadisilate / aspirin	1	2012
placebo	clopidogrel placebo	1	2006
Drug	clopidogrel treatment	1	2010
Drug	clopidogrel treatment after bare metal stent implantation	1	2007
Drug	clopidogrel/aspirin	1	2011
Drug	clopidogrel/aspirin, prasugrel/aspirin	1	2009
Drug	clopidogrel/rifampicin	1	2008
Procedure	closure device	1	2005
Diagnostic Test	cmr	1	2017
Device	cmr imaging	1	2016
Drug	cmx-2043	1	2009
Dietary Supplement	cocoa flavanols	1	2007
Behavioral	cognitive behavioral therapy (cbt)	1	2007
Other	cognitive testing	1	2016
Drug	colchicine 0.25 mg	1	2017
Drug	colchicine 0.5 mg	1	2017
placebo	colchicine placebo	1	2015
placebo	colchicine vs placebo	1	2015
Other	cold	1	2016
Drug	cold blood cardioplegia	1	2012
Drug	colesevelam	1	2008
Behavioral	collaborative care	1	2012
Behavioral	collaborative care chd	1	2014
Behavioral	collaborative care treatment	1	2009
Drug	collastat	1	2020
Drug	combination therapy with lipitor [atorvastatin]	1	2010
Drug	combination therapy with lipitor [atorvastatin]/zetia [ezetimibe]	1	2010
Other	combined - pad	1	2018
Other	combined - pad/cad	1	2018
Procedure	combined cabg	1	2011
Procedure	combined cabg/pci	1	2011
Procedure	combined exercise	1	2013
Drug	combined therapy with enoximone	1	2006
Drug	combined therapy with enoximone/esmolol	1	2006
Device	combo	1	2017
Device	combomap xt guidewire	1	2014
Other	comedy	1	2016
Behavioral	communicational program “trust”	1	2017
Drug	comparator: atorvastatin	1	2007
placebo	comparator: placebo	1	2008
Other	comprehensive assessment	1	2019
Other	comprehensive phase one rehabilitation	1	2014
Other	comprehensive therapy program for risk factor modification	1	2008
Radiation	computed coronary angiography	1	2012
Procedure	computed tomographic angiography	1	2007
Device	computed tomographic coronary angiography	1	2015
Procedure	computed tomography	1	2014
Procedure	computed tomography angiography (cardiac ct)	1	2015
Device	computer-assisted history	1	2007
Other	computer-assisted history taking	1	2007
Procedure	computer tomography angiography	1	2010
Behavioral	computerized reminders hypertension management	1	2005
Behavioral	computerized reminders medications monitoring	1	2005
Behavioral	computerized reminders osteoporosis screening	1	2005
Behavioral	computerized reminders osteoporosis screening/mgt	1	2005
Behavioral	computerized test results management application	1	2005
Procedure	concomitant mapping	1	2017
Procedure	concomitant mapping/radiofrequency ablation	1	2017
Other	connected cvr programme	1	2017
Device	conor medsystems costarâ„¢ stent (10 âµg paclitaxel)	1	2009
Device	conor medsystems costarâ„¢ stent (30 âµg paclitaxel)	1	2009
Other	conservative arm	1	2007
Procedure	conservative strategy	1	2008
Other	conservative treatment arm	1	2016
Behavioral	consult	1	2012
Behavioral	consult/behavioral intervention	1	2012
Behavioral	consultation with endocrinologist	1	2005
Other	consume 2 eggs with spinach per day	1	2020
Behavioral	consumption of dietary portfolio	1	2007
Behavioral	cont	1	2016
Other	continuous endurance training	1	2014
Other	continuous exercise training	1	2014
Device	continuous positive airway pressure	1	2014
Device	continuous positive airway pressure ventilator	1	2014
Other	continuous versus interval training	1	2008
Procedure	continuous, mechanical ventilatory support	1	2012
Other	contrast enhanced mri with gadofosveset	1	2009
Other	control (plasma)	1	2006
Behavioral	control group ：conventional exercise rehabilitation	1	2019
Device	control group training without guided exercise system at home	1	2012
Device	control stent	1	2006
Procedure	control technique	1	2018
Device	conventional	1	2020
Procedure	conventional angioplasty	1	2013
Other	conventional antidiabetic treatment	1	2006
Procedure	conventional coronary artery bypass surgery	1	2014
Drug	conventional coronary heart disease medicine	1	2018
Other	conventional cvr programme	1	2017
Procedure	conventional extracorporeal circulation	1	2017
Drug	conventional medical treatment	1	2013
Drug	conventional medicines (oxygen therapy, alfa interferon via aerosol inhalation,/lopinavir/ritonavir)/traditional chinese medicines (tcms) granules	1	2012
Device	conventional monitoring	1	2008
Procedure	conventional open svg harvesting	1	2011
Procedure	conventional strategy	1	2015
Drug	conventional strategy aspirin	1	2015
Procedure	conventional technique	1	2012
Other	conventional therapy	1	2019
Device	conventional treadmill	1	2015
Device	conventional treadmill/regadenoson	1	2015
Procedure	conventional vein harvesting	1	2017
Procedure	conventional vein harvesting technique	1	2018
Device	core size xience prime	1	2009
Device	coroflex blue (bms) followed by sequent please (deb)	1	2010
Device	coroflex please (des)	1	2010
Device	coroflexâ® isar drug-eluting stent	1	2016
Device	coroflextm please	1	2009
Procedure	coronary angiography (cag)	1	2007
Procedure	coronary angiography //- percutaneous coronary intervention	1	2019
Procedure	coronary artery bypass	1	2005
Procedure	coronary artery bypass - off-pump	1	2002
Procedure	coronary artery bypass - on-pump	1	2002
Procedure	coronary artery bypass graft	1	2007
Procedure	coronary artery bypass graft (cabg) surgery	1	2005
Procedure	coronary artery bypass graft operation	1	2011
Procedure	coronary artery bypass grafting (cabg)	1	2018
Procedure	coronary artery bypass grafting via midline sternotomy	1	2008
Procedure	coronary artery bypass surgery	1	2015
Procedure	coronary artery bypass vein grafts	1	2017
Other	coronary artery calcium (cac) scan	1	2009
Other	coronary artery disease	1	2013
Behavioral	coronary artery disease decision aid	1	2008
Device	coronary artery drug eluting stent placement	1	2005
Device	coronary artery stent placement	1	2005
Device	coronary artery stenting: absorb bvs	1	2014
Device	coronary balloons	1	2017
Procedure	coronary bypass surgery without cardiopulmonary bypass	1	2005
Procedure	coronary catheterisation	1	2007
Diagnostic Test	coronary computed tomography	1	2019
Procedure	coronary ct angiography on somatom force	1	2014
Other	coronary cta imaging	1	2015
Device	coronary drug eluting stents for pci	1	2005
Device	coronary intervention (genous stent)	1	2010
Device	coronary intervention using ivus-vh	1	2010
Device	coronary intervention using ivus-vh/fdg pet-mdct	1	2010
Procedure	coronary lithoplasty	1	2019
Device	coronary optical coherence tomography	1	2019
Procedure	coronary pci guided by ivus	1	2014
Procedure	coronary revascularization	1	2009
Device	coronary stent - tsunami	1	2012
Device	coronary stent (genous, orbusneich) with immobilised anti-cd34 antibody to capture circulating endothelial progenitor cells	1	2007
Device	coronary stent cypher	1	2010
Device	coronary stent placement	1	2006
Device	coronary stent system	1	2012
Device	coronary stent xience	1	2010
Device	coronary wires. stents	1	2017
Device	coronary wires. stents/coronary balloons	1	2017
Device	corpath 200	1	2010
Device	corpath robotic-assisted pci	1	2011
Device	corrie digital health platform	1	2018
Behavioral	counseling from diabetes educator	1	2005
Behavioral	counseling from dietician	1	2005
Other	cpr anytime education	1	2007
Dietary Supplement	cranberry juice	1	2007
Device	cre8 sirolimus-eluting stent	1	2015
Dietary Supplement	creatine	1	2007
Dietary Supplement	creatine, d-ribose, b1 vitamin,	1	2018
Dietary Supplement	creatine, d-ribose, b1 vitamin,/b6 vitamin	1	2018
Procedure	crossboss catheter	1	2015
Device	crossing of coronary artery cto	1	2015
Procedure	crush technique	1	2008
Combination Product	cswt/bmmscs	1	2017
Device	cswt/sham operation	1	2017
Diagnostic Test	ct-ffr	1	2019
Other	ct-mpi	1	2015
Other	ct-mpi/spect-mpi	1	2015
Procedure	ct angiography with high concentration contrast agent	1	2015
Procedure	ct angiography with low concentration contrast agent (270)	1	2015
Procedure	ct angiography with low concentration contrast agent (320)	1	2015
Diagnostic Test	ct as part of standard care, not a comparator	1	2018
Other	ct calcium score	1	2012
Radiation	ct coronary angiography (ctca)	1	2019
Procedure	ct guided pci	1	2010
Procedure	ct/mr	1	2009
Diagnostic Test	cta	1	2019
Diagnostic Test	cta/ffrct	1	2019
Diagnostic Test	ctca	1	2018
Radiation	ctca imaging	1	2018
Device	cto treatment device	1	2011
Other	current practice	1	2018
Device	currently common drug-eluting stent (des)	1	2016
Drug	custodiol htk	1	2012
Device	cutting	1	2015
Device	cutting balloon	1	2013
Device	cutting balloon angioplasty	1	2017
Device	cutting/scoring balloon	1	2015
Genetic	cyp2c19 test	1	2018
Device	cypher-stent (implantation of a sirolimus-eluting stent)	1	2008
Device	cypher nxt ses on bx sonic otw stent delivery system (sds)	1	2005
Device	cypher select/secss	1	2010
Device	cyphertm sirolimus-eluting coronary stent	1	2005
Other	cytology specimen collection procedure	1	2014
Device	cytosorb device	1	2014
Diagnostic Test	czt spect acquisition	1	2018
Device	czt spect camera	1	2016
Drug	daily	1	2018
Drug	dapagliflozin 10mg tab	1	2017
Drug	dapt	1	2017
Drug	dapt (aspirin and	1	2019
Drug	dapt (aspirin and/or p2y12 receptor inhibitor)	1	2019
Drug	darusentan 100 mg	1	2008
Drug	day	1	2012
Other	day light	1	2015
Dietary Supplement	day of mixed nuts	1	2018
Drug	day)	1	2005
Device	deblue stent vs. cypher stent	1	2007
Device	deblue vs cypher vs bms	1	2007
Other	decision-making tool for coronary artery disease treatment	1	2014
Behavioral	decision counseling program (dcp)	1	2008
Other	deep breathing exercises	1	2016
Other	deferral of admission for stress test	1	2017
Drug	delayed continuous use of bivalirudin	1	2019
Procedure	delayed rotational atherectomy (ra)	1	2012
Procedure	delayed treatment	1	2010
Behavioral	delirium assessment	1	2014
Device	delivery of precise levels of carbon dioxide with the ra-mrâ„¢ virtual sequential gas delivery system.	1	2014
Device	delivery of rubidium radioisotope (rb-82) using the automated pump	1	2014
Device	delivery of rubidium radioisotope (rb-82) using the automated pump/elution system	1	2014
Device	des “calypso”	1	2016
Device	des “xience prime”	1	2016
Procedure	des implantation	1	2014
Drug	desflurane	1	2019
Device	desolve	1	2016
Device	desolve cx drug eluting coronary scaffold system	1	2019
Device	desolve novolimus eluting bioresorbable coronary scaffold	1	2014
Device	desolve novolimus eluting bioresorbable coronary scaffold system	1	2014
Device	desyne bd novolimus stent system	1	2008
Device	desyne novolimus stent system	1	2008
Device	device implantation during coronary angioplasty	1	2018
Combination Product	device: medtronic resolute onyx zotarolimus-eluting coronary stent system treatment followed by one-month dapt	1	2018
Device	device: paclitaxel-coated ptca balloon catheter	1	2019
Drug	dexmedetomidine, ketamine, magnesium sulfate	1	2019
Other	diagnostic accuracy	1	2014
Diagnostic Test	diagnostic coronary angiography with non-obstructive cad	1	2018
Other	diagnostic test	1	2013
Other	diagnostic test - cardiac magnetic resonance imaging	1	2015
Other	diagnostic test - coronary angiography	1	2015
Device	diamondback 360 orbital atherectomy system	1	2010
Behavioral	diet, reducing	1	1999
Behavioral	diet, vegetarianism	1	1999
Other	dietary	1	2019
Other	dietary counseling	1	2018
Other	dietary intervention	1	2008
Behavioral	dietary supplements	1	1999
Behavioral	dietary therapy	1	2005
Other	dietary/physiotherapy	1	2019
Dietary Supplement	different amount of phytosterols are added into diets	1	2009
Device	diffuse optical tomography	1	2017
Behavioral	digital technology	1	2019
Other	dipi	1	2014
Drug	diprivan (propofol), astra-zeneca	1	2007
Behavioral	direct-to-patient tailored cardiovascular risk message system	1	2011
Procedure	direct compression	1	2005
Other	direct injection of adrcs into the left ventricle	1	2007
placebo	direct injection of placebo into the left ventricle	1	2007
Drug	discontinue dapt	1	2012
Behavioral	disease-related expressive writing	1	2010
Procedure	distal radial artery access in coronary angiography	1	2019
Procedure	distal radial artery access in coronary angiography/angioplasty	1	2019
Procedure	dk crush	1	2018
Device	dm	1	2010
Drug	docosahexanoic acid (dha)	1	2006
Other	documentary	1	2016
Other	double-low scanning	1	2018
Drug	double dose polycap	1	2011
Drug	doxycycline capsule	1	2018
Behavioral	dr. dean ornish program for reversing heart disease	1	2013
Device	drift assessment of optowire deux ffr wire (1)	1	2019
Device	drift assessment of optowire deux ffr wire (2)	1	2019
Device	driver cobalt alloy coronary stent	1	2009
Device	drug-eluting stent (des) - slow	1	2017
Device	drug-eluting stent (des) - standard(std)	1	2017
Device	drug-eluting stent/balloon angioplasty	1	2006
Device	drug eluting-stent	1	2005
Device	drug eluting balloon / bare metal stent	1	2012
Device	drug eluting balloon sequent please	1	2008
Device	drug eluting stent (zotarolimus-eluting stent)	1	2012
Device	drug eluting stent treatment	1	2010
Drug	drug infusion (bq-123)	1	2005
Drug	dual-antiplatelet therapy	1	2019
Drug	dual antiplatelet	1	2011
Drug	dual antiplatelet (dapt) therapy	1	2018
Drug	dual antipletlet therapy (dapt)	1	2014
Behavioral	dvd	1	2010
Other	dynamic physical exercise	1	2009
Device	dynamx sirolimus-eluting coronary bioadaptor system	1	2018
Other	dynasdy	1	2015
Other	e-cigarettes (high nicotine e-liquid)	1	2015
Other	e-cigarettes (low nicotine e-liquid)	1	2015
Other	e-cigarettes (nicotine free e-liquid)	1	2015
Drug	e5555	1	2006
Drug	e5555 100 mg	1	2007
Drug	e5555 200 mg	1	2007
Drug	e5555 50 mg	1	2007
Behavioral	early appointment (within 10 days)	1	2012
Other	early cardiac rehabilitation	1	2018
Device	early deflation of tr band	1	2017
Other	early discharge	1	2013
Procedure	early extubation	1	2018
Procedure	early mobilisation	1	2018
Procedure	early mobilisation/physiotherapy	1	2018
Behavioral	eat	1	2016
Other	ecg	1	2018
Other	ecg / heart rate	1	2018
Radiation	echocardiogram	1	2016
Device	echoclip	1	2016
Device	ecp therapy	1	2006
Drug	edoxaban	1	2018
Drug	edoxaban 30 mg	1	2015
Drug	edoxaban 60 mg	1	2015
Drug	edta	1	2002
placebo	edta placebo	1	2002
Behavioral	education program	1	2020
Behavioral	education/reminder	1	2003
Other	educational component	1	2016
Behavioral	educational intervention - text	1	2010
Behavioral	educational intervention - text only	1	2010
Behavioral	educational intervention - text/dvd/vhs	1	2010
Behavioral	educational intervention programme	1	2008
Behavioral	educational model	1	2016
Behavioral	educational model / follow up	1	2016
Behavioral	educational program	1	2011
Behavioral	educational program/telephone follow up	1	2011
Drug	ee	1	2008
Device	eeg monitoring	1	2019
Device	ees (xience)	1	2010
Other	egg subsitute with spinach per day	1	2020
Dietary Supplement	egg substitute	1	2011
Dietary Supplement	egg supplementation	1	2011
Other	eggs	1	2019
Combination Product	ehealth	1	2019
Drug	eicosapentaenoic acid (omega-3 fatty acid)	1	2005
Device	elective 2-stent	1	2013
Device	elective fkb	1	2013
Behavioral	electronic shared decision making (esdm) tool	1	2019
Device	elution system	1	2014
Device	emboli capturing guidewire device	1	2005
Device	emboli capturing guidewire device/with stent	1	2005
Device	emergeâ„¢ 1.20 mm ptca dilatation catheter	1	2012
Drug	empagliflozin	1	2017
Drug	empagliflozin 25 mg	1	2019
Behavioral	encompass intervention	1	2017
Other	encourage early oral food intake	1	2018
Device	endeavor des	1	2011
Device	endeavor drug eluting coronary stent	1	2008
Device	endeavor resolute	1	2009
Device	endeavor resolute (biolinx-based zotarolimus-eluting stent)	1	2010
Device	endeavor resolute stent	1	2010
Device	endeavor zotarolimus-eluting coronary stent	1	2008
Device	endeavorâ® zotarolimus eluting coronary stent system	1	2009
Device	endeavortm (zotarolimus-eluting stent)	1	2007
Behavioral	endorsed evidence summaries	1	2005
Procedure	endoscopic coronary arterial bypass	1	2019
Device	endoscopic vein harvest	1	2019
Other	endothelial function guided therapy	1	2019
Other	endurance training with constant work load	1	2011
Behavioral	enhance health lifestyle changes	1	2005
Behavioral	enhance health lifestyle changes/medication compliance	1	2005
Drug	enoxaparin (high-dose group)	1	2017
Drug	enoxaparin (single-dose pci group)	1	2017
Drug	enoxaparin (staged-dose pci group)	1	2017
Drug	enoxaparin (standard-dose group)	1	2017
Drug	enoxaparin i.v.	1	2007
Drug	enteric-coated aspirin	1	2008
Drug	epa	1	2017
Drug	epa/high dose rosuvastatin	1	2017
Procedure	epidural infusion	1	2011
Drug	eplerenone	1	2005
Drug	epoetin alpha	1	2007
Drug	epoetin beta	1	2006
Drug	eptifibatide	1	2005
Drug	er niacin	1	2007
Drug	er niacin/laropiprant	1	2007
Drug	ergocalciferol	1	2012
Drug	esmolol	1	2006
Drug	estradiol	1	2012
Drug	estrogens, conjugated	1	1999
Drug	estrogens, conjugated (usp)	1	2004
Drug	ethinyl estradiol-levonorgestrel combination	1	2012
Behavioral	ethnicity (rise)	1	2019
Other	evaluate video clinic visit prior to face-to-face usual care visit	1	2010
Device	everolimus-eluting coronary stent	1	2014
Device	everolimus-eluting stent for long lesion	1	2010
Device	everolimus-eluting stent with a durable polymer	1	2011
Device	everolimus eluting bioresorbable polymer stent	1	2014
Device	everolimus eluting stent (ees)	1	2014
Device	everolimus eluting stent (xience - ees)	1	2009
Drug	evidence-based medical care for acute coronary syndrome	1	2008
Behavioral	evidence summaries endorsed by local opinion leaders	1	2005
Drug	evolocumab 140 mg	1	2019
Drug	evolocumab 140 mg/ml [repatha]	1	2019
Device	evolution stent system	1	2010
Behavioral	ex)	1	2011
Device	excel	1	2013
Device	excel stent	1	2012
Device	excimer laser coronary atherectomy	1	2017
Drug	exenatide	1	2011
Other	exercise-based cardiac rehabilitation program	1	2011
Other	exercise compliance	1	2018
Procedure	exercise ecg	1	2015
Behavioral	exercise facilitator intervention	1	2012
Other	exercise sessions in hybrid program	1	2019
Other	exercise sessions in standard program	1	2019
Procedure	exercise stress echocardiography	1	2012
Procedure	exercise testing - coronary angiography - revascularization	1	2007
Behavioral	exercise training component	1	2013
Behavioral	exercise training for 10 weeks	1	2005
Other	exercise, aerobic (water based)	1	2014
Other	exercise/cognitive testing	1	2016
Drug	exercise/regadenoson (lexercise)	1	2010
Other	exercise/rest/cold/neutral temperature	1	2016
Device	exosealâ®	1	2011
Drug	exparel	1	2013
Drug	exparel injectable product	1	2017
Behavioral	expectation manipulation intervention	1	2011
Behavioral	experimental group ：tai chi cardiac rehabilitation program	1	2019
Behavioral	exposure to dilute diesel exhaust (300âµg	1	2007
Behavioral	exposure to dilute diesel exhaust (300âµg/m3)/filtered air	1	2007
Behavioral	exposure to sporting events	1	2008
Device	express2	1	2006
Behavioral	extended behavioral intervention	1	2016
Procedure	external counter pulsation therapy	1	2006
Other	extracorporeal photopheresis	1	2018
Drug	ezetimibe (	1	2005
Drug	ezetimibe (/) simvastatin	1	2005
Drug	ezetimibe / atorvastatin	1	2008
Other	ezetimibe / plant sterols	1	2014
Drug	ezetimibe 10 mg orally once a day	1	2017
Drug	ezetimibe 10 mg/simvastatin 20 mg	1	2007
Drug	ezetimibe 10 mg/simvastatin 40 mg	1	2007
Drug	ezetimibe 10mg	1	2007
placebo	ezetimibe placebo	1	2007
Drug	ezetimibe with simvastatin	1	2018
Drug	ezetimibe/simvastatin	1	2007
Drug	ezetimibe/simvastatin 10/20 mg	1	2007
Device	face mask	1	2008
Behavioral	familial risk assessment	1	2005
Behavioral	familial risk assessment/personalized prevention messages	1	2005
Other	family-oriented primary cardiovascular prevention	1	2018
Drug	famotidine 40mg twice daily	1	2009
Other	fan	1	2019
Other	fan / skin wetting	1	2019
Device	fantom	1	2018
Device	fantom sirolimus-eluting coronary bioresorbable scaffold	1	2015
Other	fast step test with measurement of pulmonary gas exchange	1	2018
Other	fast step test without measurement of pulmonary gas exchange	1	2018
Device	fastigial nucleus stimulation	1	2019
Drug	fdg	1	1999
Device	fdg pet-mdct	1	2010
Drug	febuxostat	1	2013
placebo	febuxostat placebo	1	2013
Behavioral	feedback friend	1	2014
Procedure	femoral technical	1	2013
Device	femosealâ®	1	2011
Drug	fentanyl, propofol	1	2019
Drug	ferric carboxymaltose	1	2018
Drug	ferumoxytol	1	2016
Diagnostic Test	ffr-based diagnostic strategy	1	2018
Device	ffr-guided coronary revascularization	1	2018
Device	ffr-guided pci	1	2018
Device	ffr-guided pci/tavi	1	2018
Procedure	ffr-guided revascularisation strategy	1	2011
Procedure	ffr-guided surgical revascularization	1	2014
Procedure	ffr (fractional flow reserve)	1	2012
Procedure	ffr guidance	1	2010
Procedure	ffr guided pci	1	2014
Device	ffr infusion microcatheter	1	2015
Device	ffr infusion microcatheter/standard intra-venous (iv) infusion	1	2015
Other	ffr measurement	1	2015
Drug	ffr measurement with iv adenoscanâ® then with regadenoson	1	2011
Device	ffr measurement, side branch angioplasty	1	2006
Procedure	ffr treatment arm	1	2016
Other	ffr via central venous line	1	2010
Other	ffr via peripheral venous line	1	2010
Other	ffrct analysis (fractional flow reserve computed tomography)	1	2012
Drug	fibrinogen	1	2009
Radiation	field of view	1	2016
Drug	filgrastim (rg-csf)	1	2008
Behavioral	filtered air	1	2007
Procedure	filtrapâ„¢	1	2011
Procedure	filtrapâ„¢ / thrombus aspiration catheter	1	2011
Behavioral	financial incentives	1	2014
Device	firebird2â® sirolimus eluting stent system	1	2014
Device	firehawk	1	2010
Device	firehawk biodegradable polymer rapamycin-eluting stent	1	2011
Device	firehawkâ„¢ stent system	1	2015
Device	firehawktm 2.25mm	1	2016
Device	firesorb	1	2016
Drug	fish oil emulsion	1	2007
placebo	fish oil supplementation vs placebo	1	2010
Device	fitbit charge 2	1	2019
Drug	fixed high potent statin therapy	1	2015
Dietary Supplement	flavanol-rich drink vs flavanol-free drink	1	2015
Other	flaxseed	1	2017
Device	floseal	1	2020
Other	flotrac measurement	1	2016
Device	fluent (vgs fluent external support device)	1	2011
Procedure	fluid loading	1	2009
Procedure	fluid restriction policy	1	2008
Procedure	fluoroscopic	1	2018
Procedure	fluoroscopic / ultrasound guidance	1	2018
Other	fluoroscopy-save group	1	2012
Drug	flurpiridaz f18	1	2011
Drug	fluvastatin	1	2005
Dietary Supplement	fmd arm	1	2019
Drug	folic acid, vitamin b12	1	2008
Drug	folic acid, vitamin b12 (cyanocobalamin)	1	2006
Drug	folic acid, vitamin b12 (cyanocobalamin), vitamin b6 (pyridoxine)	1	2006
Drug	folic acid, vitamin b12/b6/rosuvastatin	1	2008
Drug	folic acid/vitamin b6/vitamin b12	1	1999
Procedure	follow-up coronary angiography	1	2010
Other	follow-up visit m2	1	2017
Other	follow-up vsit m8	1	2017
Behavioral	follow up	1	2016
Procedure	forearm blood flow study	1	2003
Procedure	forearm radial artery access in coronary angiography	1	2019
Procedure	forearm radial artery access in coronary angiography/angioplasty	1	2019
Drug	form 1 of azd5718 tablets	1	2018
Drug	form 2 of azd5718 tablets	1	2018
Drug	form 3 of azd5718 tablets	1	2018
Drug	form 4 of azd5718 tablets	1	2018
Drug	form 5 of azd5718 tablets	1	2018
Drug	fospropofol	1	2005
Other	fraction of inspired oxygen level	1	2019
Device	fractional flow reserve	1	2005
Procedure	fractional flow reserve-guided cabg	1	2015
Diagnostic Test	fractional flow reserve with adenosine stress testing	1	2020
Procedure	free fluid infusion	1	2008
Other	full drug coverage	1	2007
Diagnostic Test	functional assessment of myocardial ischemia by icecg	1	2019
Procedure	functional testing by fractional flow reserve measurement	1	2013
Drug	gadobenate dimeglumine	1	2012
Drug	gadobutrol (gadavist, gadovist, bay86-4875)	1	2013
Drug	gadobutrol (gadovist, gadavist, bay86-4875)	1	2013
Drug	gadolinium	1	2010
Drug	gadoterate meglumine	1	2010
Device	gamma-iridium-192 catheter	1	2005
Device	gamma camera	1	2015
Dietary Supplement	garlic	1	2013
Device	gated stationary chest tomosynthesis	1	2017
Drug	gefarnate	1	2018
Device	gekotm	1	2013
Drug	gemfibrozil	1	2006
Behavioral	general sleep education	1	2016
Genetic	genetic risk counseling	1	2013
Other	genetic risk score	1	2013
Behavioral	genetic risk score for coronary risk factors	1	2011
Drug	genistein	1	2006
Other	genotype-guided therapy	1	2017
Device	genous stent implantation	1	2008
Device	genous stent implantation with paclitaxel-eluting balloon dilation	1	2008
Drug	ginkgo biloba pills	1	2018
Drug	glibenclamide 5 mg	1	2016
Device	glidesheath slender	1	2014
Drug	glimepiride upto 4 mg oral tablet	1	2018
Drug	glipizide	1	2007
Other	glitazon	1	2007
Drug	glp-1	1	2014
Drug	glucose-insulin-potassium	1	2008
Biological	glucose meter	1	2018
Drug	glutamine	1	2013
Drug	glycopyrrolate	1	2019
Behavioral	go! to sleep	1	2016
Dietary Supplement	goodbelly probiotic	1	2013
Device	gracey curettes	1	2015
placebo	grain flour placebo	1	2016
Drug	granulocyte colony-stimulating factor (g-csf)	1	2018
Dietary Supplement	grape seed extract	1	2007
Dietary Supplement	grape seed extract/ascorbic acid	1	2007
Procedure	graphic medication schedule (pill card)	1	2005
Behavioral	group based cognitive therapy	1	2020
Other	group education	1	2019
Other	group g10	1	2018
Other	group g15	1	2018
Other	group g5	1	2018
Behavioral	group support	1	2006
Drug	gs-6615	1	2013
Drug	gtn	1	2005
Device	guidant galileo intravascular radiotherapy system	1	2005
Device	guide catheter combination	1	2017
Device	guide exercise (gex-)- training	1	2012
Device	guided exercise (gex) system	1	2012
Device	guided exercise training with an easy to wear vest with electrodes to measure ecg, respiration, activity	1	2012
Device	guidelinerâ® v3 catheter, traplinerâ® catheter, turnpikeâ® catheter	1	2019
Other	half-dose isotope for nuclearstresstest	1	2012
Other	handgrip	1	2014
Behavioral	harp intervention	1	2012
Drug	hctz	1	2005
Radiation	hd-ctca with adaptive statistical iterative reconstruction (asir)	1	2013
Behavioral	health education program	1	2013
Other	health information prescription	1	2010
Behavioral	health literacy-based intervention	1	2019
Other	healthy lifestyles	1	2010
Other	healthy lifestyles/sleep education	1	2010
Other	healthy lifestyles/sleep education/pap	1	2010
Other	healthy lifestyles/sleep education/supplemental oxygen	1	2010
Other	heart rate	1	2018
Other	heart rate monitor	1	2012
Behavioral	heart rate variability (hrv) biofeedback (bf)	1	2016
Procedure	heart valve surgery	1	2012
Behavioral	hearthab application intervention	1	2016
Device	heartmate php	1	2015
Device	helios biodegradable polymer sirolimus-eluting stents	1	2019
Device	helistent titan2 (titanium coated stent)	1	2007
Other	hemodynamic	1	2011
Other	hemodynamic/biological measurements	1	2011
Drug	hepalean heparin	1	2011
Drug	hexadecasaccharide (sr123781a)	1	2005
Drug	high dose potent statin	1	2018
Drug	high dose rosuvastatin	1	2017
Dietary Supplement	high dose vitamin	1	2002
placebo	high dose vitamin placebo	1	2002
Dietary Supplement	high energy diet	1	2019
Behavioral	high intensity interval-based aerobic exercise	1	2015
Behavioral	high intensity interval training	1	2016
Other	high intensity interval training (hiit)	1	2013
Drug	high maintenance clopidogrel	1	2011
Other	high phytosterol diets	1	2009
Other	high risk	1	2013
Drug	hmg-coa reductase inhibitor	1	2011
Drug	hmg coa inhibitor	1	2006
Other	hold hypoglycemic meds	1	2011
Other	home-based cardiac rehabilitation	1	2017
Other	home-based cr	1	2018
Behavioral	home-based training with telemonitoring guidance	1	2014
Other	home cardiac rehabilitation	1	2018
Other	home cardiac rehabilitation/respiratory rehabilitation	1	2018
Other	hospital-based cr	1	2018
Other	hospital-based cr / movn application	1	2018
Other	hospital-based cr / movn application / nudge	1	2018
Drug	hs-25	1	2018
Drug	hs-25/atorvastatin	1	2018
Biological	human allogeneic mesenchymal bone marrow cells (ambmc)	1	2019
Biological	human embryonic stem cell-derived cd15	1	2013
Biological	human embryonic stem cell-derived cd15/ isl-1/ progenitors	1	2013
Drug	humanalbumin 5%	1	2010
Drug	humulin r	1	2016
Other	hvbh with oxygen	1	2014
Procedure	hybrid (midcab	1	2012
Procedure	hybrid (midcab/pci)	1	2012
Procedure	hybrid cabg	1	2009
Procedure	hybrid cabg/pci	1	2009
Behavioral	hycr	1	2018
Drug	hydrochlorothiazide (hctz)	1	2005
Drug	hydrocortisone	1	2006
Drug	hydroxychloroquine	1	2019
Drug	hypertonic sodium lactate	1	2012
Other	hyperventilation breath-hold (hvbh)	1	2014
Procedure	iabp	1	2009
Drug	ibuprofen	1	2007
Procedure	ica (invasive coronary angiography)	1	2012
Behavioral	icdm	1	2011
Device	ifr pullback with syncvision software (volcano company)	1	2020
Other	illness history	1	2016
Other	image quality	1	2014
Procedure	immediate complete pci	1	2017
Procedure	immediate rotational atherectomy (ra)	1	2012
Behavioral	impact of coronary images used during patient education on coronary artery disease	1	2011
Behavioral	impact of coronary images used during patient education on coronary artery disease/subsequent lifestyle modifications	1	2011
Drug	impact on vasp test	1	2006
Device	impella cp pvad	1	2017
Device	implantable cardioverter defibrillator	1	2014
Device	implantation of a bare metal stent	1	2010
Device	implantation of a sirolimus-eluting resorbable coronary magnesium scaffold	1	2019
Device	implantation of biolimus-eluting stents	1	2012
Device	implantation of cep magna ease model 3300tfx	1	2010
Procedure	implantation of coronary stent in bifurcation lesion	1	2011
Device	implantation of everolimus-eluting bioresorbable vascular scaffold stent	1	2012
Device	implantation of everolimus-eluting coronary stent	1	2008
Device	implantation of everolimus-eluting stents	1	2012
Device	implantation of kaname cobalt-chromium coronary stent	1	2009
Device	implantation of sirolimus-eluting coronary stent	1	2008
Procedure	in-situ	1	2018
Procedure	in-vitro hemodilution	1	2017
Other	in hospital cardiopulmonary rehabilitation	1	2009
Device	incentive spirometer	1	2016
Behavioral	increasing awareness to cardiac rehabilitation programs	1	2006
Behavioral	individual feedback	1	2014
Procedure	indocyanine green intraoperative angiogram	1	2005
Procedure	indocyanine green intraoperative angiogram/transit-time flowmetry	1	2005
Drug	infiltration of surgical wounds with local anaesthetic	1	2018
Biological	influenza vaccination: influvac (solvaypharma)	1	2006
Behavioral	information	1	2012
Behavioral	information / attention comparison	1	2012
Behavioral	information control	1	2007
Behavioral	information session	1	2008
Drug	inhalational anesthetic	1	2006
Other	inhaled anaesthetic agent	1	2012
Drug	inhibition of platelet aggregation by “brilinta”(ticagrelor)	1	2014
Drug	injection of adrc’s	1	2007
placebo	injection of placebo	1	2007
Drug	inopulse delivery system	1	2001
Other	inspirator muscle training	1	2018
Device	inspiron stent	1	2012
Drug	insulin glargine	1	2015
Behavioral	int	1	2016
Behavioral	integrated cardiovascular disease risk management.	1	2016
Behavioral	integration of a team based clinical pharmacist	1	2006
Device	intelligent terminal app	1	2018
Other	intensive control	1	2011
Behavioral	intensive exercise training	1	2010
Behavioral	intensive training	1	2014
Procedure	intentional strategy	1	2015
Behavioral	interactive voice response	1	2007
Procedure	intermittent coronary sinus occlusion	1	2012
Device	intermittent pneumatic compression of the lower extremities	1	2010
Behavioral	internet-based counselling	1	2019
Procedure	intervention (pci)	1	2006
Other	intervention group	1	2015
Drug	intra-coronary infusion	1	2006
Other	intracoronary acetylcholine provocation test	1	2009
Procedure	intracoronary bone marrow cell transfer	1	2005
Device	intracoronary stent implantation	1	2008
Procedure	intramyocardial implantation of of a novel mesenchymal precursor cell type (imp).	1	2012
Procedure	intramyocardial injection of autologous cd133	1	2007
Procedure	intramyocardial injection of autologous cd133/ marrow cells	1	2007
Genetic	intramyocardial injection of vegf-a165	1	2008
Genetic	intramyocardial injection of vegf-a165/bfgf:placebo plasmid	1	2008
Genetic	intramyocardial vegf angiogenesis (at a dose of 2 mg)	1	2005
Device	intravascular imaging (ivus	1	2017
Device	intravascular imaging (ivus/oct)	1	2017
Procedure	intravascular ultrasound of the coronary artery.	1	2012
Procedure	intravenous analgesia	1	2011
Drug	intravenous anesthetic, propofol	1	2006
Drug	intravenous dexamethasone intra-operatively	1	2018
Other	intravenous fluid challenge	1	2019
Other	intravenous glutamate infusion	1	2007
Drug	intravenous infusion of saline	1	2007
Drug	intravenous magnesium intra-operatively	1	2018
Drug	intravenous ondansetron intra-operatively	1	2018
Drug	intravenous paracetamol intra-operatively	1	2018
Drug	intravenous sedatives	1	2017
Procedure	invasive coronary angiography (ica)	1	2015
Procedure	invasive coronary treatment	1	2019
Device	investigational device	1	2013
Device	invos	1	2009
Drug	iodixanol	1	2013
Drug	iodixanol 320	1	2006
Drug	iodixanol 320 mg i	1	2005
Drug	iodixanol 320 mg i/ml	1	2005
Drug	iodixanol 320 mgi	1	2005
Drug	iodixanol 320 mgi/ml	1	2005
Drug	iomeprol	1	2010
Drug	iomeprol 350	1	2006
Drug	iopromide	1	2010
Drug	ioxaglate	1	2013
Other	iphone artery assessment	1	2015
Dietary Supplement	ipp	1	2009
Procedure	ischemia driven revascularization	1	2018
Biological	isl-1	1	2013
Drug	isoflurane 1.0 mac	1	2013
Drug	isoflurane 1.5 mac	1	2013
Drug	isoflurane 2.0 mac	1	2013
Drug	isoflurane, sevoflurane	1	2019
Drug	isoflurane, sevoflurane/desflurane	1	2019
Other	isometric exercise	1	2014
Other	isometric handgrip training (iso)	1	2017
Drug	isosorbide dinitrate	1	2012
Drug	isosorbide dinitrate 10mg tablet	1	2016
Drug	isosorbite mononitrate	1	2017
Drug	isosorbite mononitrate (ismn)	1	2017
Drug	isovue 370, 70 ml	1	2007
Drug	isovue 370, 80 ml	1	2007
Drug	isovue 370, 90 ml	1	2007
Device	itpr	1	2010
Drug	iv isotonic bicarbonate	1	2011
Drug	iv isotonic saline	1	2011
Device	ivac2l pvad	1	2017
Device	ivl coronary lithotripsy system	1	2017
Device	ivus-guided pci	1	2013
Device	ivus-guided pci/ofdi	1	2013
Device	ivus guidance	1	2020
Procedure	ivus guided percutaneous coronary angioplasty with resolute integrity stent insertion	1	2013
Device	jactax des	1	2008
Device	jactax drug eluting stent	1	2008
Device	jactax ld des	1	2008
Device	jactax ld drug eluting stent	1	2008
Procedure	jailed wire technique	1	2018
Device	janus stent	1	2006
Device	judkins 3.5l	1	2017
Device	judkins 3.5l/4r cardiac catheters	1	2017
Drug	kardogrel	1	2010
Drug	keep dapt	1	2012
Drug	kg	1	2015
Procedure	kissing balloon	1	2008
Dietary Supplement	konjac glucomannan	1	2018
Dietary Supplement	l-arg supplement	1	2018
Dietary Supplement	l-arginine	1	2007
Dietary Supplement	l-arginine/creatine	1	2007
Other	laboratory biomarker analysis	1	2014
Other	land-based exercise training	1	2016
Procedure	laryngoscopy	1	2010
Device	late deflation of tr band	1	2017
Procedure	lateral femoral cutaneous nerve blocks	1	2017
Dietary Supplement	lc-1000	1	2013
Dietary Supplement	lc-2000	1	2013
Drug	lde-paclitaxel	1	2019
placebo	lde-placebo	1	2019
Procedure	left circumflex coronary artery territories	1	2005
Other	leg exercise	1	2014
Drug	leuprolide acetate	1	2012
Drug	levosimendan	1	2005
Drug	levosimendan infusion	1	2011
Drug	lexiscan	1	2017
Device	libertã©	1	2009
Drug	lidocaine	1	2016
Behavioral	lifestyle modification	1	2010
Behavioral	lifestyle physical activity intervention	1	2012
Behavioral	lifestyle recommendations	1	2016
Behavioral	lifestyle/medication intervention	1	2010
Procedure	lima to svg bridge technique	1	2012
Drug	linagliptin	1	2015
Device	lipiscan	1	2012
Device	lipiscan coronary imaging catheter	1	2009
Device	lipiscan ivus	1	2012
Device	lipiscan/lipiscan ivus	1	2012
Drug	lipitor (atorvastatin) monotherapy	1	2010
Drug	liraglutide pen injector [victoza]	1	2017
Behavioral	lite	1	2014
Device	lithoplasty	1	2020
Drug	local anaesthetic injection	1	2017
Drug	local anesthetic	1	2017
Procedure	long introducer sheath	1	2019
Drug	louxiangdan tongxin granules	1	2011
Procedure	low-dose dobutamine tc-99-m-mibi gated spect imaging	1	2007
Other	low-dose stress mpi spect	1	2011
Drug	low-dose ticagrelor	1	2018
Device	low level laser hemotherapy	1	2018
Other	low phytosterol	1	2009
Other	low phytosterol/high phytosterol diets	1	2009
Other	lung ventilation	1	2012
Drug	m118	1	2007
Behavioral	m3)	1	2007
Device	magic-touch drug-eluting balloon	1	2015
Device	magmaris	1	2016
Drug	magnesium l-lactate	1	2006
Drug	magnesium sulfate	1	2018
Procedure	magnetic resonance imaging (mri)	1	2016
Device	magnetocardiograph	1	2005
Behavioral	mailed dvd	1	2012
Other	maintenance of physical exercise	1	2019
Procedure	mammarioradial graft (y-graft)	1	2013
Behavioral	management of stress	1	2020
Procedure	marrow cells	1	2007
placebo	matching liraglutide-placebo pre-filled pens	1	2017
placebo	matching placebo	1	2009
Biological	mcrciâ® stem cells	1	2019
Procedure	mdct	1	2007
Procedure	mdct calcium score	1	2006
Procedure	mdct of the coronary arteries.	1	2006
Procedure	mdct/coronary angiography	1	2007
Device	mdt-4107 drug eluting stent	1	2009
Device	mdt-4107 zotarolimus-eluting coronary stent	1	2010
Procedure	measure of hemodynamic indices in a stenosed coronary artery using a pressure wire	1	2019
Other	measure of psychiatric condition	1	2016
Other	measure of social conditions	1	2016
Drug	medi5884	1	2017
Biological	medi6012	1	2015
Device	medical device hemopatch-peg-coated collagen patch	1	2017
Behavioral	medication compliance	1	2005
Other	medication education tool	1	2006
Behavioral	medication intervention	1	2010
Behavioral	medication review	1	2014
Procedure	meditation	1	2001
Behavioral	medium-intensity minimally-directive counseling	1	2006
Drug	medroxyprogesterone	1	1999
Drug	medroxyprogesterone 17-acetate	1	2004
Drug	medroxyprogesterone 2.5 mg daily	1	2006
Device	medtronic bifurcation stent system	1	2008
Device	medtronic coronary drug-coated balloon catheter	1	2017
Device	medtronic endeavor coronary stent system	1	2008
Device	medtronic endeavor resolute	1	2008
Device	medtronic resolute onyx zotarolimus-eluting coronary stent system	1	2017
Drug	melatonin 3 mg	1	2019
Dietary Supplement	menaquinone-7 (vitamin k2)	1	2009
Other	mental stress protocol	1	2016
Diagnostic Test	mental stress test	1	2019
Device	meres100 sirolimus eluting bioresorbable vascular scaffold system	1	2015
Genetic	mesenchymal stem cells	1	2010
Device	mesh	1	2013
Drug	metformin 1000 mg oral tablet	1	2018
Drug	metformin only	1	2012
Drug	metformin xl	1	2014
Drug	metformin, glimepiride, insulin	1	2007
Drug	metformin/vildagliptin	1	2012
Drug	methylnaltrexone	1	2015
Behavioral	mgt	1	2005
Other	mhealth-cr	1	2019
Behavioral	mi	1	2014
Behavioral	mi/medication review	1	2014
Procedure	mics cabg	1	2018
Drug	midazolam	1	2016
Drug	milrinone	1	2009
Drug	min	1	2015
Behavioral	mindfulness based stress reduction	1	2013
Behavioral	mindfulness based stress reduction (mbsr)	1	2017
Behavioral	mindfulness based stress reduction class	1	2005
Procedure	mini-crush stenting	1	2016
Procedure	miniaturized extracorporeal circulation	1	2017
Procedure	minimally invasive bypass surgery	1	2005
Device	mio slice	1	2019
Drug	mipomersen	1	2008
Drug	misoprostol	1	2014
Device	mistent	1	2015
Device	mistent (mt005) coronary artery stent	1	2016
Device	mistent des	1	2011
Device	mistent ses	1	2010
Procedure	mitral valve repair	1	2008
Procedure	mitral valve repair with annuloplasty	1	2008
Procedure	mitral valve replacement	1	2008
Drug	ml [praluent]	1	2018
Drug	ml [repatha]	1	2019
Behavioral	mobile application	1	2017
Behavioral	mobile health application	1	2015
Behavioral	moderate consumption of fruit juice rich in polyphenolics	1	2006
Other	moderate continuous exercise training	1	2014
Behavioral	moderate continuous training	1	2010
Behavioral	moderate daily consumption of beer	1	2006
Behavioral	moderate daily consumption of red wine	1	2006
Behavioral	moderate intensity continuous training	1	2017
Drug	modified-release dipyridamole	1	2005
Drug	modified-release dipyridamole/aspirin	1	2005
Diagnostic Test	modified allen’s test	1	2019
Other	modified allen test	1	2015
Procedure	modified ultrafiltration	1	2010
Device	modular cardiopulmonary bypass circuit	1	2013
Drug	molsidomine	1	2006
Other	mononuclear cells from autologous bone marrow	1	2013
Drug	montelukast	1	2006
Drug	morphine	1	2015
Other	motivational interviewing (mi)	1	2019
Behavioral	motivational interviewing (mint)	1	2012
Behavioral	motivational social support from nurse	1	2019
Behavioral	motivational social support from nurse with additional support from significant other	1	2019
Behavioral	movie	1	2012
Behavioral	moving	1	2005
Other	movn application	1	2018
Behavioral	movn mobile app	1	2018
Drug	mpsk3169a	1	2012
Procedure	mr	1	2009
Other	mr-only imaging on biograph mmr scanner	1	2014
Procedure	mr imaging of the coronary arteries	1	2006
Other	mr imaging on the siemens vida 3t mr scanner	1	2014
Procedure	mr perfusion guidance	1	2010
Other	mr scan	1	2016
Procedure	mri	1	2008
Procedure	ms-ct coronary angiography	1	2006
Biological	msc	1	2011
Behavioral	multi-disciplinary disease management approach	1	2009
Procedure	multidetector computed tomography	1	2011
Other	multidetector computed tomography - 64 detectors	1	2008
Procedure	multidetector computed tomography coronary angiography	1	2006
Radiation	multidetector computed tomography scanning	1	2007
Behavioral	multidisciplinary palliative care team met with patient	1	2006
Procedure	multiple-pass hemofiltration	1	2011
Procedure	multiple arterial grafting	1	2017
Other	music therapy	1	2012
Procedure	myocardial contrast echocardiography	1	1999
Procedure	myocardial ct perfusion	1	2014
Device	myocardial iq-spect imaging applied to scintigraphic imaging	1	2015
Procedure	myocardial perfusion imaging	1	2009
Procedure	myocardial perfusion imaging scan	1	2007
Device	myocardial perfusion mri	1	2013
Other	myocardial perfusion scan	1	2017
Procedure	myocardial protection techniques	1	2005
Device	myovista device	1	2015
Drug	n-13 ammonia	1	2011
Drug	n-hydroxy-nor-arginine	1	2013
Drug	n(2)-l-alanine l-glutamine dipeptide	1	2011
Drug	nacl	1	2013
Behavioral	navigation by a health worker	1	2007
Device	nc balloon	1	2019
Other	ncep step 1 diet	1	2009
Other	ncep step 1 diet/almonds	1	2009
Drug	nebivolol	1	2008
Drug	neostigmine	1	2019
Drug	nesiritide	1	2008
Behavioral	network construction	1	2019
Other	neutral temperature	1	2016
Drug	nh(3)	1	1999
Drug	niacin/laropiprant	1	2010
Drug	niaspan	1	2007
Dietary Supplement	nicotinamide riboside (nr)	1	2016
Drug	nicotine patch	1	2017
Drug	nifedipine	1	2005
Device	nirs/ivus	1	2016
Device	nirx(tm) paclitaxel-coated conformer coronary stent system	1	2006
Drug	nitrates, clopidogrel, aspirin, statins	1	2010
Drug	nitric oxide/inopulse delivery system	1	2001
Drug	nitrous oxide/placebo	1	2008
Device	no-numoâ„¢ high vacuum body cavity drainage system	1	2007
Procedure	no-touch svg harvest vs conventional svg harvest technique	1	2010
Other	no almonds	1	2009
Behavioral	no exposure to sporting events	1	2008
Device	no face mask	1	2008
Other	no ischemic preconditioning	1	2015
Behavioral	no moving	1	2005
Other	no nitrous oxide	1	2007
Other	no physical activity monitors	1	2010
Diagnostic Test	no routine stress testing	1	2017
Other	no screening	1	2018
Drug	non-arb	1	2005
Other	non-pet medical management	1	2019
Other	non-ventilated group	1	2012
Other	non invasive cardiac imaging	1	2009
Other	non periodized exercise training regime	1	2017
Other	noninvasive ventilation	1	2016
Behavioral	nordic walking	1	2016
Drug	normal saline flush, 0.9% injectable solution	1	2018
Drug	normal saline solution	1	2011
Other	notices	1	2009
Drug	novel strategy aspirin	1	2015
Device	noya cocr biodegradable coating sirolimus-eluting stent system	1	2014
Device	nse balloon	1	2019
Behavioral	nutritional	1	2008
Behavioral	nutritional/behavioral program a	1	2008
Behavioral	nutritional/behavioral program b	1	2008
Dietary Supplement	nuts	1	2014
Drug	oac alone	1	2013
Procedure	obturator nerve blocks	1	2017
Device	oct	1	2016
Device	oct-guided paclitaxel drug-coated balloon angioplasty	1	2020
Device	oct-guided pci	1	2018
Device	oct-guided pci with ees	1	2012
Device	oct-guided pci with ees/bes	1	2012
Procedure	oct-pci	1	2018
Device	oct guide	1	2012
Device	oct)	1	2017
Device	oct/cmr imaging	1	2016
Other	octa (angiography by tomography in optical coherence)	1	2018
Device	ofdi-guided pci	1	2013
Device	ofdi-guided pci/ivus	1	2013
Device	ofdi imaging	1	2007
Procedure	off-pump bypass surgery	1	2011
Other	off-pump cabg	1	2018
Procedure	off-pump cabg.	1	2018
Procedure	off-pump coronary-artery bypass grafting	1	2014
Procedure	off-pump coronary artery bypass grafting	1	2005
Procedure	off pump cabg	1	2009
Dietary Supplement	olive oil	1	2014
Drug	omacor (omega-3-acid ethyl esters)	1	2007
Drug	omega-3-acid ethyl esters 90	1	2006
Dietary Supplement	omega-3 fatty acid supplement	1	2009
Drug	omega 3	1	2012
Dietary Supplement	omega 3 acid ethyl esters	1	2012
Device	omegaâ„¢ monorail coronary stent system	1	2011
Drug	omeprazole	1	2013
Drug	omeprazole, 20mg twice daily	1	2009
Drug	omnipaque	1	2013
Procedure	on-pump bypass surgery	1	2011
Other	on-pump cabg	1	2018
Procedure	on-pump cabg.	1	2018
Procedure	on-pump coronary-artery bypass grafting	1	2014
Other	once ounce per day of walnuts	1	2013
Device	one-catheter concept	1	2016
Device	one stent technique	1	2013
Device	one stent technique / elective fkb	1	2013
Device	one stent technique alone	1	2013
Behavioral	online decision aid	1	2016
Procedure	opcabg with partial clamp	1	2017
Procedure	opcabg with partial clamp applying carbon dioxide	1	2017
Procedure	open radial artery harvest	1	2013
Other	open vein harvest	1	2019
Behavioral	opinion leader generated	1	2005
Behavioral	opinion leader generated/endorsed evidence summaries	1	2005
Device	opn strategy	1	2018
Device	optical coherence tomography	1	2014
Device	optical coherence tomography-guided pci with bioresorbable vascular scaffold	1	2015
Device	optical coherence tomography (c7 xr dragonfly )	1	2012
Device	optical coherence tomography evaluations	1	2017
Other	optimal medical therapy (omt)	1	2014
Drug	optimal medical treatment	1	2014
Drug	optimal medicamentous treatment	1	2016
Drug	optimarkâ®	1	2013
Procedure	optimisation of the result of intracoronary stenting according to specific algorithm	1	2016
Drug	optimizing asa	1	2010
Drug	optimizing asa/clopidogrel treatment	1	2010
Behavioral	optimizing processes of care	1	2006
Drug	optimizing therapeutic treatments	1	2006
Drug	or p2y12 receptor inhibitor)	1	2019
Drug	oral gabapentin pre-op	1	2018
Drug	oral hypoglycemic agents	1	2009
Drug	oral l-arginine supplementation (at a dose of 6 g	1	2005
Drug	oral l-arginine supplementation (at a dose of 6 g/day)	1	2005
Drug	oral lansoprazole pre-op	1	2018
Device	oral prophylaxis	1	2012
Drug	oral sirolimus	1	2007
Device	orbital atherectomy	1	2017
Device	orbital atherectomy system (oas)	1	2016
Other	organic atlas cedar wood essential oil (cedrus atantica)	1	2019
Device	orsiro - drug eluting coronary stent	1	2010
Device	orsiro des	1	2015
Device	orsiro drug eluting stent	1	2014
Other	orthostatic group	1	2015
Device	osiro hybrid drug-eluting stent	1	2013
Other	other: multidetector computed tomography - 320 detectors	1	2009
Behavioral	out-patient rehabilitation at the hospital	1	2006
Drug	overencapsulated caffeine	1	2009
Drug	oxycodone 10mg	1	2019
Device	oxycon mobile	1	2019
Drug	oxygen gas	1	2017
Drug	oxytocin	1	2008
Drug	ozone	1	2018
Procedure	p.i.o.s.	1	2017
Diagnostic Test	p2ry12 assay	1	2018
Drug	p2y12 antagonist monotherapy	1	2014
Device	paclitaxel-eluting stent (taxus)	1	2008
Device	paclitaxel-eluting taxus(tm)	1	2005
Device	paclitaxel coated balloon catheter	1	2006
Device	paclitaxel eluting balloon catheter	1	2018
Device	paclitaxel eluting ptca balloon catheter (sequent please)	1	2008
Device	paclitaxel eluting taxus stent (boston scientific)	1	2008
Drug	paclitaxel nanoparticle albumin bound	1	2004
Behavioral	paco intervention for avr patients	1	2018
Behavioral	paco intervention for cabg patients	1	2018
Behavioral	paco intervention for mvr patients	1	2018
Drug	pactimibe, cs-505	1	2005
Drug	padma 28	1	2012
Behavioral	paleolithic diet vs mediterranean diet	1	2007
Procedure	palpation	1	2012
Drug	pantoprazole 40mg once daily	1	2009
Other	pap	1	2010
Procedure	papillary muscle approximation	1	2017
Drug	paracetamol	1	2007
Behavioral	participatory patient care planning	1	2016
Behavioral	partners together in health (path) intervention	1	2009
Device	pas-port automated proximal anastomosis system	1	2006
Procedure	passive leg raising (45 degree leg elevation for 1-2 min)	1	2010
Other	patent hemostasis	1	2011
Other	patent hemostasis/heparin	1	2011
Procedure	patient-controlled epidural analgesia	1	2011
Other	patient-targeted feedback	1	2013
Drug	paxil-cr	1	2005
Device	pcb ptca	1	2019
Procedure	pci- drug eluting stents	1	2006
Device	pci for in-bioresorbable scaffold stenosis	1	2017
Other	pci on the basis of coronary angiography	1	2010
Device	pci with bes under angio-guide	1	2012
Device	pci with bes under angio-guide/oct guide	1	2012
Combination Product	pci with biomatrix alphaâ„¢ stent	1	2019
Combination Product	pci with comboâ„¢ stent	1	2019
Procedure	pci with des	1	2005
Device	pci with dynamic coronary roadmap	1	2019
Device	pci with ees under angio-guide	1	2012
Device	pci with ees under angio-guide/oct guide	1	2012
Procedure	pci with ivus guidance	1	2011
Device	pci without dynamic coronary roadmap	1	2019
Procedure	pci without ivus guidance	1	2011
Procedure	pci)	1	2012
Device	pe	1	2013
Device	pe/investigational device	1	2013
Procedure	pedicled lima	1	2018
Behavioral	peer mentor	1	2015
Biological	pegfilgrastim	1	2009
Drug	pentoxifylline	1	2012
Procedure	percutaneous coronary angioplasty	1	2006
Procedure	percutaneous coronary angioplasty/intervention (pci)	1	2006
Device	percutaneous coronary intervention (dreams) stenting	1	2013
Device	percutaneous coronary intervention (ng promus)	1	2012
Device	percutaneous coronary intervention (pci) with paclitaxel-eluting stent (taxus express) placement	1	2007
Device	percutaneous coronary intervention (xience v stent)	1	2007
Device	percutaneous coronary intervention biotronik orsiro des	1	2011
Procedure	percutaneous coronary intervention for complex lesion	1	2017
Procedure	percutaneous coronary intervention using bare metal stents	1	2014
Procedure	percutaneous coronary intervention using drug eluting stents	1	2014
Device	percutaneous coronary intervention using r-one assistance	1	2019
Device	percutaneous coronary intervention with implantation of amphilimus-eluting stents for coronary artery disease.	1	2019
Device	percutaneous coronary intervention with implantation of everolimus-eluting stents for coronary artery disease.	1	2019
Device	percutaneous coronary intervention with new generation fully resorbable scaffold	1	2015
Device	percutaneous coronary intervention with nobori biolimus-eluting stent implantation	1	2014
Procedure	percutaneous coronary intervention with stent implantation	1	2018
Device	percutaneous coronary intervention with taxus stent	1	2006
Device	percutaneous coronary stenting	1	2005
Procedure	percutaneous transluminal angioplasty	1	2006
Procedure	percuteneous coronary intervention	1	2018
Drug	perflutren lipid microsphere injectable suspension	1	2005
Other	perfusion cardiac magnetic resonance imaging	1	2009
Other	perfusion cmr for detection of coronary artery disease	1	2009
Other	periodized exercise training regime	1	2017
Procedure	periodontal therapy	1	2010
Procedure	periodontal treatment: srp	1	2003
Other	peripheral muscle training	1	2018
Procedure	peripheral nerve block	1	2017
Radiation	peripheral quantitative computed tomography of the radius	1	2013
Device	permanent polymer everolimus-eluting stent (xience, promus)	1	2008
Device	permanent polymer limus-eluting stent	1	2010
Device	permanent polymer rapamycin-eluting stent (cypher)	1	2008
Other	personal health record	1	2013
Drug	personalized dapt duration	1	2019
Behavioral	personalized prevention messages	1	2005
Behavioral	personalized reminders	1	2019
Other	pet-mr imaging on biograph mmr scanner	1	2014
Other	pet imaging	1	2006
Drug	pet mpi	1	2017
Radiation	pet scan	1	2016
Diagnostic Test	pet stress test	1	2019
Device	pet/ct	1	2006
Other	pet/mr scan	1	2016
Drug	pexelizumab in conjunction with cabg	1	2004
Behavioral	pharmacist counselling session with a motivational interview	1	2013
Drug	pharmacological stress agents	1	2017
Device	phase signal recorder	1	2016
Other	phcvrs intervention	1	2013
Behavioral	physical activity	1	2005
Device	physical activity monitors	1	2010
Procedure	physician taken history	1	2007
Other	physiological saline	1	2018
Device	physiologically-guided strategy	1	2017
Other	physiotherapy exercises	1	2015
Dietary Supplement	phytosterol enhanced soy based beverage	1	2009
Other	phytosterols	1	2009
Other	phytosterols / ezetimibe	1	2009
Procedure	picso	1	2011
Device	piezoelectric ultrasonic scaler (frequency of 28-36 khz)	1	2015
Drug	pioglitazone 15 mg tablet	1	2016
Drug	pioglitazone 30 mg	1	2011
placebo	placebo (for rvx000222)	1	2015
placebo	placebo (for sarpogrelate)	1	2014
placebo	placebo (saline)	1	2009
Drug	placebo / aspirin	1	2010
Drug	placebo / isosorbite mononitrate (ismn)	1	2017
placebo	placebo 40 mg	1	2006
placebo	placebo arm	1	2010
placebo	placebo capsules	1	2009
placebo	placebo colesevelam	1	2008
placebo	placebo comparator:	1	2008
placebo	placebo comparator: lactated ringer’s	1	2012
Device	placebo comparator: lactated ringer’s/subject’s blood	1	2012
placebo	placebo control	1	2009
placebo	placebo for atorvastatin	1	2019
placebo	placebo for clopidogrel	1	2006
placebo	placebo for colestipol	1	1999
placebo	placebo for ezetimibe	1	2019
placebo	placebo for lovastatin	1	1999
placebo	placebo for prasugrel	1	2006
placebo	placebo influenza vaccine	1	2006
placebo	placebo infusion	1	2011
placebo	placebo injection	1	2017
placebo	placebo intake	1	2015
placebo	placebo iv	1	2015
placebo	placebo juice	1	2008
placebo	placebo matching azd5817 oral suspension	1	2017
placebo	placebo niacin	1	2008
placebo	placebo of isosorbide dinitrate	1	2012
placebo	placebo of quick-acting heart reliever	1	2012
placebo	placebo of sheng mai capsules	1	2009
placebo	placebo of sheng mai capsules,	1	2009
placebo	placebo of xuefu zhuyu capsules	1	2009
Drug	placebo of xuefu zhuyu capsules/placebo of sheng mai capsules	1	2009
placebo	placebo pills	1	2018
placebo	placebo sc	1	2015
placebo	placebo suspension	1	2008
placebo	placebo tablet	1	2012
placebo	placebo to match azd6140	1	2008
placebo	placebo to telcagepant	1	2011
placebo	placebo, double	1	2007
Drug	placebo/aspirin	1	2009
Drug	placebo/sugar pill	1	2005
placebo	placebo: diluent used to suspend auto-cd34	1	2012
Biological	placebo: diluent used to suspend auto-cd34/ cells	1	2012
Diagnostic Test	platelet acetyl coenzyme a carboxylase analysis in cad	1	2017
Drug	plavix	1	2010
Drug	plavix (clopidogrel bisulfate)	1	2009
Drug	plavixâ®	1	2011
Behavioral	plus	1	2014
Device	poba	1	2010
Genetic	point-of-care genetic screening with subsequent prasugrel administration to cyp2c19*2 carriers	1	2010
Drug	policosanol	1	2011
Drug	policosanol/dual antiplatelet	1	2011
Device	polymer-free amphilimus-eluting stents	1	2017
Device	polymer-free des (drug eluting stent)	1	2015
Device	polymer-free stent	1	2016
Device	polymer-free, rapamycin-eluting stent	1	2006
Device	polymer based zotarolimus-eluting stent (endeavor resolute)	1	2008
Drug	pomwonderful juice	1	2008
Other	position change applied at different times	1	2018
Procedure	positron emission tomography: fdg viability imaging	1	2006
Behavioral	post-operative cardiac rehabilitation	1	2016
Drug	post-operative gabapentin analgesia	1	2018
Drug	post-operative ondansetron anti-emesis	1	2018
Drug	post-operative oral paracetamol analgesia	1	2018
Diagnostic Test	post-pci coronary physiology measurements	1	2017
Dietary Supplement	post cabg	1	2014
Behavioral	postoperative cardiac rehabilitation	1	2016
Device	powerassert rf wire in crossing coronary in-stent chronic total occlusions	1	2010
Drug	ppc heparin	1	2011
Drug	prasugrel 10mg	1	2013
Drug	prasugrel 30 mg	1	2014
Drug	prasugrel loading dose	1	2012
Drug	prasugrel maintenance dose	1	2012
placebo	prasugrel placebo	1	2006
Drug	pravastatin 20 mg	1	2014
Behavioral	pre-habilitation	1	2018
Dietary Supplement	pre-operative carbohydrate preload drink	1	2018
Behavioral	pre/post-operative cardiac rehabilitation	1	2016
Diagnostic Test	pre/post-pci coronary physiology measurements	1	2017
Drug	prednisone	1	2006
Drug	pregrel (clopidogrel resinate)	1	2009
Drug	pregrelâ®	1	2011
Drug	premarin .625 mg daily	1	2006
Drug	premarin .625 mg daily/medroxyprogesterone 2.5 mg daily	1	2006
Other	preoperative coronary angiography	1	2014
Other	preoperative exercise training	1	2018
Device	presillion cobalt chromium stent	1	2008
Behavioral	pressure pain sensitivity measure followed bu acupressure	1	2012
Device	pressure wire certus, st. jude medical, usa	1	2016
Device	prevena device (group a)	1	2012
Behavioral	prevention consult	1	2012
Procedure	previous coronary ct angiography on 2nd generation ct scanner	1	2014
Procedure	primary pci with thrombectomy	1	2011
Procedure	primary pci without thrombectomy	1	2011
Procedure	primary percutaneous coronary intervention	1	2013
Device	pro-kinetic energy stent	1	2012
Behavioral	problem solving treatment in primary care (pst-pc)	1	2015
Drug	probucol	1	2011
Device	probucol-eluting stent (isar stent)	1	2008
Biological	progenitors	1	2013
Drug	progestins	1	1999
Drug	proleukin	1	2017
Device	promus	1	2010
Device	promus coronary stent system	1	2009
Device	promus des	1	2017
Device	promus element (everolimus-eluting stent)	1	2011
Device	promus element everolimus-eluting coronary stent system	1	2011
Device	promus element plus	1	2012
Device	promus element/coronary stent system	1	2012
Device	promus elementâ„¢	1	2009
Device	promus(tm) element (tm) stent system	1	2010
Procedure	prone imaging	1	2015
Drug	propofol 1.0mcg	1	2013
Drug	propofol 2.0mcg	1	2013
Drug	propofol 3.0mcg	1	2013
Genetic	prospective genotype testing	1	2012
Procedure	provisional approach	1	2013
Procedure	provisional t stenting	1	2008
Drug	psychiatric treatment with escitalopram	1	2019
Drug	psychiatric treatment with sertraline	1	2019
Behavioral	psycho-educative component	1	2013
Behavioral	psychodynamic motivation	1	2011
Behavioral	psychodynamic motivation/training program (pmt)	1	2011
Other	psychometric analysis	1	2019
Behavioral	psychotherapy	1	2008
Other	ptca	1	2005
Device	ptca balloon catheter	1	2009
Device	ptca of coronary de novo lesion pcb	1	2019
Device	ptca of coronary de novo lesion scb	1	2019
Device	ptca with stent placement	1	2011
Behavioral	public education	1	2019
Behavioral	public education/network construction	1	2019
Other	pump-assisted cabg	1	2018
Procedure	pump-assisted cabg.	1	2018
Device	pvc chest tube	1	2007
Drug	pycnogenol	1	2008
Other	pyramid-training	1	2011
Other	pyramid training	1	2014
Dietary Supplement	q10-150	1	2013
Dietary Supplement	q10-300	1	2013
Diagnostic Test	qfr	1	2018
Diagnostic Test	qfr-based diagnostic strategy	1	2018
Procedure	qfr-guided cabg	1	2018
Device	qfr-guided strategy	1	2019
Behavioral	quality of life questionnaires	1	2018
Drug	quercetin	1	2019
Other	questionnaire	1	2018
Other	questionnaire administration	1	2014
Drug	quick-acting heart reliever	1	2012
Device	quikclot radial pad	1	2018
Drug	quinapril	1	2005
Device	qvanteq bioactive coronary stent	1	2014
Device	radi pressure wire (pressure wire assessment)	1	2010
Procedure	radial approach	1	2017
Procedure	radial artery	1	2005
Procedure	radial artery graft	1	2003
Procedure	radial artery/saphenous vein grafts randomized to either right coronary/left circumflex coronary artery territories	1	2005
Procedure	radial technical	1	2013
Procedure	radiofrequency ablation	1	2017
Drug	radioisotope	1	2014
Radiation	radiolabeled (99tc) ec-dg (ethylenedicysteine-deoxyglucose	1	2013
Drug	ramipril	1	2008
Drug	ramipril 5 mg	1	2016
Drug	ramipril hoe498	1	2017
Procedure	randomised to guidelines group	1	2011
Procedure	randomized left versus right radial artery approach	1	2012
Drug	ranitidine	1	2013
placebo	ranolazine placebo	1	2011
Device	rapamycin-eluting stent	1	2006
Device	rapamycin-eluting stent with biodegradable polymer	1	2006
Device	rapamycin-eluting stent with permanent polymer	1	2006
Device	rapamycin / probucol-eluting stent (isar stent)	1	2008
Device	rapamycin target-eluting coronary stent system	1	2016
Device	rapamycin target-eluting coronary stent systems (38mm)	1	2016
Device	rapamycin/17beta estradiolvalerat-eluting stent	1	2006
Other	rapid-vt software guided ablation	1	2018
Other	rate of perceived exertion	1	2012
Radiation	real-time 3-dimensional dynact	1	2014
Drug	red yeast rice	1	2006
Procedure	referral	1	2003
Procedure	refill reminder postcard	1	2005
Drug	reg1	1	2008
Drug	regadenoson (lexercise)	1	2010
Drug	regadenoson (lexiscan)	1	2010
Drug	regadenoson central - peripheral	1	2012
Drug	regadenoson central -central	1	2012
Drug	regadenoson mri	1	2012
Drug	regadenoson mri myocardial blood flow	1	2009
Drug	regadenoson myocardial perfusion imaging	1	2009
Drug	regadenoson peripheral - central	1	2012
Drug	regadenoson peripheral - peripheral	1	2012
Drug	regular human insulin	1	2015
Other	regular screening	1	2018
Other	rehabilitation	1	2017
Behavioral	rehabilitation at home	1	2006
Behavioral	rehabilitation in institution	1	2006
Combination Product	reimmugen	1	2016
Other	relaxation music	1	2013
Behavioral	reminder	1	2003
Procedure	remote ischaemic preconditioning	1	2010
Other	remote ischemic conditioning	1	2013
Procedure	remote ischemic postconditioning	1	2009
Other	removal of fentanyl from peri-procedural analgesia	1	2016
Other	reports	1	2009
Other	reports/notices	1	2009
Behavioral	resilience, stress,	1	2019
Behavioral	resilience, stress,/ethnicity (rise)	1	2019
Behavioral	resistance training	1	2016
Device	resmed s8 (auto-cpap)	1	2007
Device	resolute integrity (zotarolimus-eluting stent)	1	2011
Device	resolute integrity zotarolimus eluting stent	1	2014
Device	resolute integrityâ„¢ zotarolimus-eluting coronary stent system(34	1	2017
Device	resolute integrityâ„¢ zotarolimus-eluting coronary stent system(34/38 mm)	1	2017
Device	resolute onyx stent - 2.0 mm	1	2015
Device	resolute onyx stent - 2.25 mm - 4.0 mm	1	2015
Device	resolute stent treatment	1	2012
Device	resolute zotarolimus-eluting coronary stent	1	2008
Device	resolute zotarolimus-eluting coronary stent system	1	2011
Device	resolute zotarolimus-eluting stent	1	2015
Other	respiratory rehabilitation	1	2018
Other	rest	1	2016
Other	rest five hours	1	2012
Other	rest three hours	1	2012
Drug	resten-mp	1	2005
Dietary Supplement	resveratrol (3, 4â´, 5 trihydroxystilbene)	1	2014
Genetic	retrospective genotype testing	1	2012
Drug	revacept 160 mg	1	2017
Drug	revacept 80 mg	1	2017
Device	revascularisation	1	2013
Procedure	reverse tap	1	2018
Device	rezolve stent	1	2010
Diagnostic Test	rfr	1	2020
Procedure	rfr guided cabg	1	2020
Device	ric	1	2018
Drug	rifabutin oral capsule	1	2018
Drug	rifampicin	1	2008
Procedure	right internal thoracic artery composite grafting	1	2010
Drug	rilonacept	1	2006
Drug	rimonabant (sr141716)	1	2005
Drug	ringer’s solution	1	2013
Procedure	ripple mapping guided ischaemic vt ablation	1	2019
Behavioral	risk result	1	2013
Drug	rituximab injection	1	2017
Drug	rivaroxaban (xarelto, bay59-7939)	1	2011
Drug	rivaroxaban (xarelto, bay59-7939)/ufh	1	2011
Drug	rivaroxaban 2.5 mg oral tablet	1	2019
Drug	rivaroxaban 2.5mg tablet	1	2018
Drug	ro4905417	1	2010
Procedure	robot assisted percutaneous cardiovascular intervention	1	2020
Procedure	robotic-assisted coronary surgical revascularization	1	2006
Behavioral	role modeling	1	2006
Other	room light	1	2015
Device	root planing	1	2012
Drug	ropivacaine	1	2019
Drug	rosiglitazone (4 mg)	1	2012
Drug	rosiglitazone (4 mg)/day	1	2012
Drug	rosuvastatin-esomeprazole	1	2009
Drug	rosuvastatin-omeprazole	1	2009
Drug	rosuvastatin-pantoprazole	1	2009
Drug	rosuvastatin-ranitidine	1	2009
Drug	rosuvastatin (crestor)	1	2007
Drug	rosuvastatin 10 mg	1	2017
Drug	rosuvastatin 10 mg/ezetimibe 10 mg orally once a day	1	2017
Drug	rosuvastatin 10mg	1	2018
Drug	rosuvastatin 20 mg orally once a day	1	2017
Drug	rosuvastatin alone	1	2014
Drug	rosuvastatin calcium 20 mg oral tablet	1	2016
Drug	rosuvastatin calcium 40mg	1	2009
Drug	rosuvastatin tablet	1	2016
Drug	rosuvastatin/atorvastatin/simvastatin/clopidogrel	1	2005
Drug	rosuvastatin/fenofibrate	1	2014
Procedure	rotablation	1	2019
Device	rotablator	1	2013
Device	rotablator rotational atherectomy system	1	2016
Device	rotational atherectomy by rotablator	1	2016
Drug	routine dual antiplatelet	1	2011
Device	routine measurement of ffr	1	2016
Other	routine referral (at 5 weeks)	1	2012
Diagnostic Test	routine stress testing	1	2017
Radiation	rubidium pet	1	2012
Device	safeseal(tm) hemostasis patch	1	2007
Other	safflower oil	1	2012
Drug	salsalate	1	2008
Procedure	saphenous vein composite grafting	1	2010
Procedure	saphenous vein graft	1	2003
Procedure	saphenous vein grafts randomized to either right coronary	1	2005
Device	sapphire ii pro	1	2017
Drug	sar247799	1	2018
Device	savr	1	2018
Drug	saxagliptin	1	2012
Drug	sb-480848	1	2005
Drug	sb-681323	1	2006
Device	scaffold	1	2014
Device	scb ptca	1	2019
Behavioral	schultz autogenic training	1	2020
Device	scintigraphic imaging	1	2015
Device	scoreflex nc scoring ptca catheter	1	2018
Device	scoring balloon	1	2015
Device	scoring ptca balloon (nse alpha)	1	2018
Other	secondary prevention	1	2014
Behavioral	secondary prevention program for coronary heart disease	1	2005
Other	secondary prevention/cardiac rehabilitation clinic	1	2014
Device	secss	1	2010
Behavioral	sedentary prompts from a vtap device	1	2016
Biological	selected cd 133	1	2008
Biological	selected cd 133/ cells	1	2008
Drug	selected cell product	1	2016
Drug	selected form (form 2 - 5) of azd5718 tablets	1	2018
Other	selective screening	1	2014
Behavioral	self-management intervention	1	2013
Drug	semaglutide 2 mg	1	2019
Drug	semaglutide 2 mg/1.5 ml subcutaneous solution	1	2019
Device	sequent please drug eluting balloon catheter with paclitaxel	1	2019
Device	sequent(r) please coated balloon	1	2011
Device	sequentâ® please paclitaxel-coated balloon	1	2014
Drug	serelaxin	1	2013
Device	ses	1	2008
Drug	sestamibi. reconstitution with sodium pertechnetate (99mtc)	1	2011
Drug	sevoflurane 1	1	2015
Drug	sevoflurane 2	1	2015
Other	sexual rehabilitation	1	2013
Other	sham cardiac shock wave (control group)	1	2017
Other	sham comparator	1	2017
Behavioral	sham comparator: neutral writing	1	2010
Other	sham controll	1	2019
Device	sham operation	1	2017
Procedure	sham transcutaneous acupoint electrical stimulation	1	2018
Behavioral	shared care model	1	2012
Drug	sheng mai capsules	1	2009
Drug	sheng mai capsules/placebo of xuefu zhuyu capsules	1	2009
Device	shockwave coronary rx lithoplastyâ® system	1	2015
Other	short	1	2018
Procedure	short introducer sheath	1	2019
Other	short/fast step test with measurement of pulmonary gas exchange	1	2018
Other	short/fast step test without measurement of pulmonary gas exchange	1	2018
Other	significant extracoronary arterial stenoses in all arterial beds	1	2007
Drug	sildenafil	1	2018
Drug	simivastatin	1	2019
Drug	simvastatin (	1	2007
Drug	simvastatin (/) ezetimibe	1	2007
Drug	simvastatin 10	1	2007
Drug	simvastatin 20mg	1	2007
Drug	simvastatin 20mg/ezetimibe 10mg	1	2007
Drug	simvastatin 80mg	1	2007
placebo	simvastatin placebo	1	2007
Drug	single antiplatelet agents	1	2018
Procedure	single arterial graft	1	2017
Drug	single dose polycap	1	2011
Procedure	single photon emission computed tomography (spect) myocardial perfusion imaging (mpi)	1	2012
Device	sirolimus-eluting coronary stent (cypher)	1	2008
Device	sirolimus-eluting stent for short lesion	1	2010
Device	sirolimus-eluting stent system	1	2015
Device	sirolimus-eluting stent with a bioresorbable polymer (orsiro)	1	2011
Device	sirolimus-eluting stent, zotarolimus-eluting stent	1	2007
Device	sirolimus-eluting, heparin-coated cocr balloon-expandable stent	1	2005
Device	sirolimus coated bx velocity stent - fast release	1	2005
Device	sirolimus coated bx velocity stent - slow release	1	2005
Device	sirolimus coated bx velocityâ„¢	1	2005
Procedure	sirolimus drug-eluting stent implantation via provisional t stenting	1	2016
Procedure	sirolimus drug-eluting stent via active transfer of plaque	1	2016
Device	sirolimus eluting coronary stent	1	2014
Device	sirolimus eluting coronary stent system (biomime)	1	2012
Device	sirolimus eluting cypher select(tm)	1	2005
Device	sirolimus eluting drug stent	1	2014
Device	sirolimus eluting stent inspiron	1	2015
Device	sirolimus target eluting bioresorbable vascular scaffold	1	2016
Device	siso model-based predictive closed-loop system	1	2008
Drug	sitagliptin/acarbose	1	2013
Procedure	skeletonization of the internal thoracic artery	1	2005
Procedure	skeletonized lima	1	2018
Other	skin wetting	1	2019
Other	sleep education	1	2010
Other	slow-paced walking	1	2015
Other	smartphone	1	2012
Behavioral	smartphone application	1	2019
Diagnostic Test	smartphone assessment	1	2019
Behavioral	smbg	1	2013
Behavioral	smoking cessation counseling	1	2017
Behavioral	smt-enhanced cardiac rehabilitation	1	2009
Diagnostic Test	soc cardiovascular evaluation	1	2019
Behavioral	soccer	1	2012
Other	sodium chloride	1	2011
Dietary Supplement	sodium nitrate	1	2011
Drug	sodium nitrite	1	2017
Drug	sodium valproate	1	2018
Drug	somatotropin	1	2007
Drug	somatropin	1	2020
Device	somvc001 vascular conduit solution	1	2014
Device	sonolysis	1	2014
Other	spect-mpi	1	2015
Radiation	spect imaging	1	2016
Drug	spect mpi	1	2017
Procedure	spinal analgesia	1	2005
Procedure	spinal analgesia/anesthesia for coronary artery surgery	1	2005
Device	sprinter legend 1.25mm balloon catheter	1	2009
Biological	stage 1-high dose vm202ry	1	2017
Biological	stage 1-low dose vm202ry	1	2017
Biological	stage 1-middle dose vm202ry	1	2017
Biological	stage 2-high dose vm202ry	1	2017
Biological	stage 2-low dose vm202ry	1	2017
placebo	stage 2-placebo	1	2017
Procedure	staged complete pci	1	2017
Device	standard 6- french radial sheath	1	2014
Other	standard cardiac imaging	1	2010
Behavioral	standard cardiac rehabilitation	1	2009
Other	standard cardiac workup	1	2014
Device	standard catheter	1	2016
Other	standard control	1	2011
Drug	standard dapt	1	2019
Drug	standard dapt duration	1	2019
Other	standard discharge	1	2013
Device	standard dose non-contrast enhanced ct	1	2015
Drug	standard dose rosuvastatin	1	2017
Device	standard freebreathing spect-mpi	1	2015
Drug	standard insulin treatment	1	2014
Device	standard intra-venous (iv) infusion	1	2015
Other	standard of care for heart failure	1	2013
Other	standard of care for heart failure/coronary artery disease	1	2013
Other	standard of care heparin-dosed saline	1	2014
Drug	standard of care lipid therapy	1	2012
Other	standard outpatient observation	1	2017
Device	standard strategy	1	2018
Other	standard technique	1	2012
Behavioral	standard therapeutic support	1	2019
Drug	statin recapture therapy	1	2012
Drug	statins, ezetimibe	1	2007
Device	statseal	1	2017
Device	statseal with tr band	1	2019
Biological	stem cell	1	2005
Device	stem cell injection	1	2006
Procedure	stem cell mobilization	1	2002
Biological	stem cell therapy	1	2006
Device	stent implantation	1	2010
Procedure	stent technique: provisional fkbt	1	2010
Procedure	stent technique: routine fkbt	1	2010
Device	stent, medronic resolute integrity	1	2015
Device	stent/scaffold	1	2014
Procedure	stenting/minimally invasive bypass surgery	1	2005
Other	stenting/omt	1	2010
Behavioral	stepping up to health	1	2008
Device	sternalock blue closure system	1	2013
Other	strength training	1	2013
Behavioral	strength training intervention	1	2005
Procedure	stress	1	2005
Procedure	stress-echocardiography	1	2008
Procedure	stress echocardiography with dobutamine	1	1999
Behavioral	stress management	1	2005
Other	stress mpi spect	1	2011
Procedure	stress nuclear myocardial perfusion imaging	1	2008
Device	stress single photon emission computed tomography	1	2014
Device	study group	1	2017
Device	subgingival scaling	1	2012
Device	subgingival scaling/root planing	1	2012
Device	subject’s blood	1	2012
Device	subjects receiving desyne novolimus eluting css	1	2013
Behavioral	subsequent lifestyle modifications	1	2011
Procedure	substrate modification	1	2009
Drug	sugammadex	1	2019
Drug	sulfasalazine	1	2007
Device	super high-pressure nc ptca balloon (opn nc)	1	2018
Behavioral	supervised exercise on a stationary bicycle, 3-5 days a week	1	2005
Other	supervised physical exercise training x2 weekly for 8 weeks	1	2012
Other	supervised physical exercise training x3 weekly for 12 weeks	1	2012
Dietary Supplement	supplement	1	2015
Dietary Supplement	supplement post cabg	1	2014
Dietary Supplement	supplement pre	1	2014
Dietary Supplement	supplement pre cabg	1	2014
Dietary Supplement	supplement pre/post cabg	1	2014
Dietary Supplement	supplement/placebo intake	1	2015
Drug	supplemental insulin (insulin aspart)	1	2015
Drug	supplemental insulin (insulin lispro)	1	2015
Other	supplemental oxygen	1	2010
Drug	supplementation, food	1	1999
Behavioral	support programme	1	2005
Behavioral	supportive therapy	1	2011
Device	supralimus-coreâ„¢	1	2008
Device	supralimus-coreâ„¢ sirolimus eluting coronary stent	1	2010
Device	supralimusâ® sirolimus-eluting coronary stent	1	2011
Drug	suprane (desflurane), baxter	1	2007
Device	surveillance arm	1	2010
Device	suture wire	1	2013
Drug	suved	1	2016
Other	symptom-limited exercise	1	2009
Device	synergy 48 mm	1	2017
Device	synergy des implantation during coronary angioplasty	1	2018
Device	synergy investigational device	1	2013
Device	synergy stent system	1	2015
Device	synergyâ„¢ stent	1	2017
Behavioral	systematic education in the reduction of the risk estimate to cardiovascular events	1	2008
Behavioral	systemchange	1	2014
Procedure	szabo t-stenting technique	1	2018
Procedure	t-graft	1	2010
Procedure	t-provisional stenting	1	2016
Procedure	t-stenting technique	1	2018
Other	tai chi exercises	1	2019
Behavioral	talking rx	1	2015
Drug	tamsulosin oral capsule	1	2019
Drug	targeted ldl-c goal statin	1	2015
Device	tavi	1	2018
Device	taxus	1	2009
Device	taxus elementâ„¢ paclitaxel-eluting stent system	1	2015
Device	taxus express 2â„¢	1	2007
Device	taxus express paclitaxel-eluting coronary stent system	1	2006
Device	taxus libertã¨	1	2008
Device	taxus libertã¨â„¢ paclitaxel drug-eluting stent	1	2008
Device	taxus libertã© stent system	1	2006
Device	taxus libertã©â„¢-sr	1	2006
Device	taxus liberte	1	2007
Device	taxus liberte paclitaxel-eluting coronary stent system	1	2011
Device	taxus paclitaxel-eluting stent	1	2005
Device	taxus stent/cypher stent	1	2006
Device	taxusâ„¢ element long stent	1	2013
Device	taxusâ„¢ express2	1	2006
Device	taxusâ„¢ express2â„¢ paclitaxel eluting coronary stent system	1	2005
Device	taxusâ„¢ libertã¨â„¢ des	1	2008
Device	taxusâ® express2â„¢ paclitaxel eluting coronary stent	1	2005
Device	taxusâ® libertã©â„¢	1	2010
Device	taxusâ® libertã©â„¢ paclitaxel eluting coronary stent system	1	2007
Device	tcd-10023 drug eluting stent	1	2013
placebo	tcm granule placebo	1	2011
Drug	tcm granule placebo/western basis treatment	1	2011
placebo	tcm granules placebo	1	2011
Radiation	technetium	1	2009
Radiation	technetium tc99m sestamibi	1	2011
Radiation	technetium tc99m sestamibi /technetium tc99m tetrafosmin	1	2011
Radiation	technetium tc99m tetrafosmin	1	2011
Drug	technetium tc99m tetrofosmin injections	1	2006
Other	tee measurement	1	2016
Drug	telcagepant	1	2011
Behavioral	tele cardiac rehabilitation	1	2017
Other	telehealth	1	2020
Other	telemonitoring	1	2017
Behavioral	telephone-based physical activity counseling program	1	2005
Behavioral	telephone based peer support	1	2014
Behavioral	telephone follow up	1	2011
Behavioral	telephone interview	1	2014
Drug	telmisartan	1	2008
Drug	telmisartan 40 mg	1	2006
Drug	telmisartan, bisoprolol	1	2007
Device	temporary spinal cord stimulation	1	2018
Drug	testosterone undecanoate	1	2005
Other	tetracosactin	1	2006
Drug	tetraspan	1	2011
Drug	tetrofosmin)	1	2011
Behavioral	text message	1	2017
Behavioral	text message reminders	1	2017
Drug	thallous chloride t1-201	1	2006
Other	the mediterranean-like diet	1	2017
Device	the synergyâ® stent	1	2018
Behavioral	therapeutic education	1	2013
Drug	thienopyridine for 3 months	1	2012
Drug	thienopyridine therapy	1	2010
Drug	thiopentone	1	2011
Procedure	thrombus aspiration catheter	1	2011
Drug	ticagrelor / aspirin	1	2013
Drug	ticagrelor 270mg	1	2013
Drug	ticagrelor 360mg	1	2013
Drug	ticagrelor 60	1	2014
Drug	ticagrelor 60 mg	1	2017
Drug	ticagrelor 90	1	2014
Drug	ticagrelor loading dose	1	2014
Drug	ticagrelor tablets	1	2007
Drug	ticagrelor/aspirin	1	2020
Device	tiger cardiac catheter	1	2017
Behavioral	timing of initiation of cardiac rehabilitation	1	2017
Drug	tissue plasminogen activator	1	1999
Device	tivoli	1	2015
Drug	tongxinluo	1	2012
Drug	topical lidocaine	1	2016
Drug	topical nitroglycerine	1	2016
Other	topical treatment	1	2009
Drug	torcetrapib	1	2005
Drug	torcetrapib/atorvastatin	1	2005
Drug	tp10	1	2004
Device	tr band	1	2017
Device	tr band only	1	2019
Procedure	track light	1	2010
Procedure	traditional acupuncture	1	2007
Procedure	traditional cardiac rehabilitation	1	2013
Behavioral	traditional training	1	2014
Other	training / glitazon	1	2007
Other	training / metformin	1	2007
Behavioral	training program (pmt)	1	2011
Drug	trandolapril	1	2005
Other	trans-femoral	1	2013
Other	trans-radial	1	2013
Dietary Supplement	trans-resveratrol	1	2018
Procedure	transcutaneous acupoint electrical stimulation	1	2018
Drug	transdermal nicotine patch	1	2009
Biological	transepicardial with transseptal cd 133	1	2016
Biological	transepicardial with transseptal cd 133/ implantation	1	2016
Procedure	transfemoral	1	2016
Procedure	transfemoral coronary angiography	1	2013
Procedure	transfemoral coronary angiography/intervention	1	2013
Other	transition to unsupervised phase	1	2019
Procedure	transplantation of iron-bearing nanoparticles	1	2010
Procedure	transplantation of nanoparticles	1	2010
Procedure	transradial	1	2016
Procedure	transradial coronary angiography	1	2013
Procedure	transradial coronary angiography/intervention	1	2013
Other	transtheoretical model-based (ttm - based) intervention	1	2019
Other	transtheoretical model-based (ttm - based) intervention/motivational interviewing (mi)	1	2019
Device	transthoracic echocardiography	1	2015
Device	transthoracic echocardiography imaging	1	2018
Other	treadmill aerobic exercise	1	2017
Other	treadmill aerobic exercise in orthostatic position	1	2017
Other	treadmill aerobic exercise in supine position	1	2017
Other	treadmill aerobic exercise/water intake in orthostatic position	1	2017
Other	treadmill aerobic exercise/water intake in supine position	1	2017
Procedure	treadmill exercise test	1	2003
Drug	treatment a	1	2019
Other	treatment as usual (tau)	1	2011
Drug	treatment b	1	2019
Drug	treatment c	1	2019
Biological	treatment group	1	2007
Device	tri staple technology stapler	1	2009
Device	trimaxx coronary stent placement	1	2008
Drug	trimetazidine	1	2006
Device	truefidelity	1	2019
Procedure	trust technique	1	2017
Device	tryton	1	2010
Device	tryton side branch stent with main branch des	1	2010
Behavioral	tulppa rehabilitation	1	2018
Procedure	turp	1	2019
Drug	ufh	1	2011
Device	ultimaster with 6 to 12 months dapt	1	2015
Device	ultimasterâ® drug-eluting stent	1	2016
Diagnostic Test	ultra low-dose ctac	1	2018
Device	ultra low dose non-contrast enhanced ct	1	2015
Other	ultrasound guided left stellate ganglion block	1	2020
Drug	un-fractionated heparin	1	2005
Device	uncoated bx velocity stent	1	2005
Procedure	undersizing mitral annuloplasty	1	2017
Other	upright position	1	2010
Drug	urokinase	1	2012
Device	use of bioresorbable vascular scaffolds	1	2014
Behavioral	use of healthpals (telemedicine supported by digital health platform)	1	2017
Other	use of hearthab application followed by usual care	1	2017
Procedure	use of radial artery for access for a coronary angiography	1	2019
Procedure	use of radial artery for access for a coronary angiography/intervention	1	2019
Combination Product	uspio labeled msc injection	1	2018
Other	usual cardiological care	1	2008
Other	usual care followed by the use of hearthab application	1	2017
Other	usual care group	1	2018
Behavioral	usual care treatment	1	2009
Other	usual coverage	1	2007
Behavioral	usual text messages	1	2019
Device	uvb phototherapy	1	2009
Other	valve repair procedure with cabg.	1	2018
Other	valve repair procedure without cabg.	1	2018
Drug	vancomycin	1	2013
Drug	varenicline	1	2009
Drug	varespladib (a-002)	1	2007
Drug	vascepa	1	2016
Behavioral	vascular access decision aid	1	2009
Device	vascular access site closure (7f ensure)	1	2007
Device	vascular closure device	1	2006
Device	vascular compression device- radar tm-short clamp time	1	2014
Device	vascular compression device radar tm-long clamp time	1	2014
Other	vegetarian diet followed by meat diet	1	2016
Other	vegetarian diet followed by meat diet/vice versa	1	2016
Genetic	vegf-a165 plasmid	1	2005
Biological	vegf-d gene transfer	1	2009
Procedure	vein harvest	1	2005
Other	venous blood sampling	1	2013
Other	ventilatory muscle training (tremven)	1	2017
Drug	verapamil sr	1	2005
Drug	verapamil sr/trandolapril/hydrochlorothiazide (hctz)	1	2005
Drug	vericiguat (bay1021189) / isosorbite mononitrate	1	2017
Device	verifynow	1	2009
Drug	very-short dapt less than 1 month after pci	1	2019
Device	vest	1	2017
Device	vest external support	1	2015
Behavioral	vhs	1	2010
Drug	via-2291	1	2006
Drug	vicagrel 5mg	1	2018
Drug	vicagrel 6mg	1	2018
Drug	vicagrel 7.5mg	1	2018
Other	vice versa	1	2016
Behavioral	video decision aid	1	2016
Drug	vildagliptin 50 mg oral tablet	1	2018
Behavioral	virtual cardiac rehabilitation program	1	2018
Other	virtual tour in coronary computed tomography - 360â° counselling environment	1	2018
Drug	vitamin b12/folic acid	1	2008
Drug	vitamin b6	1	1999
Drug	vitamin b6 (pyridoxine)	1	2006
Drug	vitamin d3 50000 unt oral capsule	1	2018
Biological	vm202ry	1	2011
Drug	volatile anesthetic	1	2011
Drug	volume replacement	1	2010
Drug	vorapaxar	1	2017
Drug	vorapaxar, aspirin,	1	2017
Drug	vorapaxar, aspirin,/clopidogrel	1	2017
Drug	vorapaxar/aspirin	1	2017
Drug	vorapaxar/clopidogrel	1	2017
Procedure	vt ablation	1	2009
Behavioral	walking	1	2013
Other	walking programme	1	2016
Other	water-based exercise training	1	2016
Other	water intake in orthostatic position	1	2017
Other	water intake in supine position	1	2017
Drug	water pill daily	1	2005
Behavioral	web-based prevention program	1	2019
Other	website	1	2017
Other	weight-loss compliance	1	2018
Other	weight loss	1	2012
Dietary Supplement	weight loss treatment	1	2012
Behavioral	weight reduction	1	2007
Drug	western basis treatment	1	2011
Dietary Supplement	wheat bran	1	2018
Device	with stent	1	2005
Procedure	without kissing balloon angioplasty “leave alone”	1	2008
Behavioral	women@heart program	1	2017
Other	worksheet to facilitate goal-setting	1	2009
Other	worksheet to facilitate goal-setting/action plans	1	2009
Other	x-ray coronary angiography	1	2012
Drug	xenon/propofol	1	2013
Device	xience coronary artery stent	1	2016
Device	xience des	1	2015
Device	xience prime	1	2012
Device	xience prime des	1	2012
Device	xience prime eecss	1	2014
Device	xience prime everolimus-eluting stent system	1	2015
Device	xience prime long lesion (ll)	1	2009
Device	xience prime sv eecss	1	2010
Device	xience primeâ®	1	2013
Device	xience primeâ®/xience xpeditionâ„¢	1	2013
Device	xience v (everolimus-eluting stent)	1	2010
Device	xience v everolimus eluting coronary stent system (xience v eecss)	1	2010
Device	xience vâ® eecss	1	2010
Device	xience vâ® everolimus eluting coronary stent system	1	2007
Device	xience xpedition everolimus eluting stent	1	2014
Device	xience xpeditionâ„¢	1	2013
Device	xience/promus des	1	2017
Device	xienceâ„¢	1	2013
Device	xlimus	1	2015
Device	xlimus des implantation during coronary angioplasty	1	2018
Drug	xuefu-zhuyu capsule	1	2019
Drug	xuefu zhuyu capsules	1	2009
Drug	xuefu zhuyu capsules/placebo of sheng mai capsules,	1	2009
Procedure	y-graft	1	2018
Drug	yangxinshi pill	1	2018
Device	yinyi stent	1	2011
Device	yukon choice stent system	1	2006
Device	zes resolute (endeavor resolute)	1	2010
Drug	zetia [ezetimibe]	1	2010
Device	zotarolimus-eluting stent for acs	1	2010
Device	zotarolimus-eluting stent for acs/dm	1	2010
Device	zotarolimus eluting stent (endeavor resoulte - zes resolute)	1	2009

Interventions over Time

Weekly studies for each intervention

Studies by Country

Country	Study_Count
United States	436
NA	133
China	124
Canada	98
Korea, Republic of	92
Germany	89
United Kingdom	78
Denmark	61
Brazil	46
France	46
Japan	46
Italy	44
Switzerland	42
Netherlands	33
Norway	26
Sweden	24
Greece	21
Poland	21
Russian Federation	19
Spain	17
Belgium	16
Finland	13
United States|Canada	13
India	12
Israel	10
Taiwan	9
Austria	8
Iran, Islamic Republic of	8
Australia	5
Egypt	5
Turkey	5
Croatia	4
Czech Republic	4
Hong Kong	4
Slovenia	4
Argentina	3
Belgium|Netherlands	3
Colombia	3
Indonesia	3
Lebanon	3
Pakistan	3
Portugal	3
Colombia|Italy	2
Denmark|Sweden	2
Ecuador	2
France|Germany	2
Hungary	2
Ireland	2
Italy|Switzerland	2
Jordan	2
Mexico	2
New Zealand	2
Romania	2
Thailand	2
United States|Australia	2
United States|Canada|Denmark	2
United States|Ireland|Netherlands|Sweden	2
United States|Japan	2
United States|New Zealand|Singapore	2
United States|United Kingdom	2
Argentina|Australia|Austria|Bahrain|Bangladesh|Belgium|Bulgaria|Czechia|Denmark|Estonia|France|Germany|Hungary|India|Israel|Italy|Japan|Korea, Republic of|Netherlands|North Macedonia|Poland|Saudi Arabia|Serbia|Singapore|Slovenia|Spain|Sweden|Switzerland|United Kingdom|Vietnam	1
Argentina|Australia|Austria|Belgium|Brazil|China|Denmark|France|Germany|Greece|Hungary|India|Israel|Italy|Latvia|Malaysia|Netherlands|Norway|Poland|Portugal|Russian Federation|South Africa|Spain|Switzerland|United Kingdom|Venezuela	1
Argentina|Austria|Belgium|Brazil|Denmark|France|Germany|Hungary|Italy|Latvia|Netherlands|Norway|Poland|Spain|Switzerland	1
Argentina|Belgium|Brazil|Hungary|Netherlands|Poland|Russian Federation|Spain	1
Australia|Austria|Belgium|Bulgaria|France|Hong Kong|Ireland|Italy|Korea, Republic of|Latvia|Lithuania|Malaysia|Netherlands|New Zealand|Norway|Poland|Singapore|Slovakia|Spain|Sweden|Switzerland|Thailand|United Kingdom	1
Australia|Belgium|Brazil|Denmark|France|Germany|Netherlands|Poland	1
Australia|Belgium|Brazil|Germany|Netherlands|New Zealand|Poland|Switzerland	1
Australia|Belgium|Denmark|France|Germany|Netherlands|New Zealand|Portugal|Switzerland|United Kingdom	1
Australia|Belgium|Denmark|France|Netherlands|New Zealand|Poland|Switzerland	1
Australia|Belgium|Denmark|France|New Zealand|Poland|Spain|Sweden|United Kingdom	1
Australia|Belgium|New Zealand	1
Australia|Brazil|Singapore	1
Australia|France|Netherlands|Sweden|United Kingdom	1
Australia|Latvia|New Zealand	1
Australia|Malaysia|New Zealand|Singapore	1
Australia|New Zealand|Singapore	1
Austria|Belgium|China|Germany|Hong Kong|Italy|Netherlands|Portugal|Singapore|Spain|Switzerland|Taiwan|United Kingdom	1
Austria|Belgium|Denmark|France|Germany|India|Italy|Netherlands|New Zealand|Poland|South Africa|Spain|Switzerland	1
Austria|Belgium|France|Germany|Netherlands|United Kingdom	1
Austria|Belgium|Germany|Netherlands|Poland|Spain|Sweden|Switzerland	1
Austria|Belgium|United States|Argentina|Australia|Brazil|Canada|China|Czechia|Denmark|Finland|France|Germany|Grenada|Hungary|Ireland|Israel|Italy|Korea, Republic of|Netherlands|New Zealand|Poland|Puerto Rico|Slovakia|South Africa|Spain|Sweden|Switzerland|United Kingdom	1
Austria|Czechia|Denmark|Germany|Hungary|Ireland|Italy|Latvia|Lithuania|Poland|Portugal|Romania|Serbia|Spain|United Kingdom	1
Austria|Denmark|France|Germany|Greece|Netherlands|Portugal|Spain	1
Austria|Denmark|Germany|Hungary|Switzerland	1
Austria|Denmark|Germany|Switzerland	1
Austria|France|Germany|Israel|Italy|Malaysia|Netherlands|Poland|Spain|Thailand|United Kingdom	1
Austria|France|Germany|Italy|Netherlands|Switzerland|United Kingdom	1
Austria|Germany|Israel|United Kingdom	1
Austria|Germany|Switzerland	1
Austria|Hungary	1
Austria|United States|Argentina|Australia|Belgium|Brazil|Bulgaria|Canada|Chile|China|Croatia|Czech Republic|Estonia|Finland|France|Germany|Greece|India|Ireland|Israel|Italy|Korea, Republic of|Latvia|Lithuania|Malaysia|Mexico|Netherlands|Poland|Romania|Russian Federation|Singapore|Slovakia|South Africa|Spain|Sweden|Switzerland|Turkey|United Kingdom	1
Belgium|Brazil	1
Belgium|Brazil|Czechia|Latvia|Macedonia, The Former Yugoslav Republic of|Netherlands|Poland|Spain|United Kingdom	1
Belgium|Brazil|Denmark|Germany|Netherlands|Singapore|Spain|Switzerland	1
Belgium|Brazil|Denmark|Germany|New Zealand|Poland	1
Belgium|Czech Republic|France|Germany|Netherlands|Spain|Sweden|United Kingdom	1
Belgium|Czechia|France|Germany|Netherlands|Sweden|Switzerland	1
Belgium|Denmark|Estonia|Finland|Germany|Ireland|Italy|Latvia|Netherlands|Norway|Poland|Sweden|United Kingdom	1
Belgium|Denmark|France|Germany|Italy|Netherlands|Spain|Sweden|United Kingdom	1
Belgium|Finland|Netherlands|Switzerland|United Kingdom	1
Belgium|France|Germany|Netherlands|Poland|Switzerland|United Kingdom	1
Belgium|France|Luxembourg|Netherlands	1
Belgium|France|Netherlands|New Zealand|Sweden|United Kingdom	1
Belgium|Germany	1
Belgium|Germany|Israel|Sweden	1
Belgium|Germany|Netherlands|Switzerland	1
Belgium|Germany|Netherlands|United Kingdom	1
Belgium|Italy	1
Belgium|Italy|Netherlands	1
Belgium|New Zealand	1
Belgium|United Kingdom	1
Brazil|Germany	1
Brazil|Greece|Poland|Spain|United States|Argentina|Australia|Bulgaria|Canada|China|Czechia|Denmark|Estonia|France|Germany|Hungary|Japan|Korea, Republic of|Latvia|Lithuania|Malaysia|Mexico|Netherlands|Portugal|Romania|Russian Federation|Slovakia|South Africa|Sweden|Turkey|Ukraine|United Kingdom	1
Brazil|Indonesia|Macedonia, The Former Yugoslav Republic of|Malaysia	1
Cameroon|Canada|Italy|Spain|United Kingdom|	1
Canada|Czech Republic|France|Poland|Romania|Russian Federation|Slovakia	1
Canada|New Zealand	1
Chile	1
China|Hong Kong	1
China|Korea, Republic of	1
Czechia	1
Czechia|Denmark|Germany|Switzerland	1
Czechia|Germany|Hungary|Netherlands|Norway|Poland|Singapore|Sweden	1
Czechia|United States|Australia|France|Germany|Hungary|New Zealand|Poland|Romania|United Kingdom	1
Denmark|Estonia|Finland|France|Norway|Spain|Sweden|United Kingdom	1
Denmark|Finland|Latvia|Sweden	1
Denmark|Finland|Sweden	1
Denmark|France|Germany|Italy|Japan|Lithuania|Netherlands|Poland|Spain|Sweden|Switzerland	1
Denmark|France|Germany|Italy|Latvia|Serbia|Spain|United Kingdom	1
Denmark|France|Germany|Netherlands	1
Denmark|Germany|Netherlands	1
Denmark|Italy|Japan|Netherlands|Spain|United Kingdom	1
Denmark|Latvia	1
Denmark|Netherlands|Spain	1
Denmark|Netherlands|Spain|Sweden	1
Denmark|Poland	1
Denmark|Spain	1
Finland|France|Germany|Italy|Netherlands|Poland|Spain|Switzerland|United Kingdom	1
France|Germany|Italy|Netherlands	1
France|Germany|Italy|Serbia|Spain	1
France|Germany|Italy|Spain|Switzerland	1
France|Germany|Netherlands	1
France|Netherlands|United Kingdom	1
Germany|Australia|Austria|Belgium|Brazil|Bulgaria|Canada|Denmark|France|Hungary|Italy|Netherlands|Poland|Portugal|Singapore|Spain|Switzerland|United Kingdom	1
Germany|Belgium	1
Germany|Italy|Jordan	1
Germany|Jordan|Spain	1
Germany|Latvia	1
Germany|Moldova, Republic of|Netherlands	1
Germany|Switzerland	1
Germany|United Kingdom	1
Greece|Hungary|Ireland|Poland|Portugal|Russian Federation|Slovakia|Switzerland|	1
Hong Kong|Taiwan	1
Ireland|Austria|Belgium|Canada|China|Czech Republic|France|Germany|Greece|India|Israel|Italy|Malaysia|Netherlands|New Zealand|Portugal|Singapore|South Africa|Spain|Sweden|Switzerland|Thailand|United Kingdom	1
Ireland|United Kingdom	1
Italy|Netherlands	1
Italy|Spain	1
Italy|United Kingdom	1
Japan|Philippines	1
Kazakhstan	1
Latvia	1
Lithuania	1
Malaysia	1
Netherlands|Russian Federation	1
Netherlands|Spain	1
Netherlands|Switzerland	1
Netherlands|United States|Argentina|Australia|Bulgaria|Canada|Czechia|Denmark|France|Germany|Hungary|Italy|Korea, Republic of|Poland|Russian Federation|Spain|Sweden|Taiwan|United Kingdom	1
Netherlands|United States|Australia|Czechia|Germany|Hungary|Italy	1
New Zealand|United States|Latvia|United Kingdom	1
Oman	1
Palestinian Territory, occupied	1
Poland|Argentina|Australia|Austria|Belgium|Brazil|Canada|China|Denmark|France|Germany|India|Israel|Italy|Japan|Malaysia|Netherlands|New Zealand|Singapore|South Africa|Spain|Sweden|Switzerland|Taiwan|United Kingdom	1
Poland|United Kingdom	1
Poland|United States|Australia|Canada|China|Czech Republic|Denmark|France|Hungary|Mexico|Netherlands|Spain|United Kingdom	1
Puerto Rico	1
Slovakia	1
South Africa	1
Spain|United States|Argentina|Australia|Bulgaria|Canada|Denmark|Estonia|France|Germany|Hungary|India|Netherlands|New Zealand|Pakistan|Romania	1
Spain|United States|Australia|Austria|Belgium|Canada|France|Germany|Ireland|Italy|Netherlands|South Africa|Switzerland|United Kingdom|	1
Sri Lanka	1
Trinidad and Tobago	1
Ukraine	1
United States|Argentina	1
United States|Argentina|Australia|Austria|Belgium|Brazil|Canada|China|Egypt|France|Germany|Hungary|India|Israel|Italy|Japan|Lithuania|Malaysia|Mexico|Netherlands|New Zealand|North Macedonia|Peru|Poland|Portugal|Romania|Russian Federation|Saudi Arabia|Serbia|Singapore|South Africa|Spain|Sweden|Switzerland|Taiwan|Thailand|United Kingdom	1
United States|Argentina|Australia|Belgium|Brazil|Canada|Chile|Czech Republic|France|India|Korea, Republic of|Mexico|Netherlands|Poland|Portugal|Russian Federation|Spain|Turkey	1
United States|Argentina|Australia|Belgium|Brazil|Canada|France|Hungary|Italy|Mexico|Netherlands|Poland|Russian Federation|Spain	1
United States|Argentina|Australia|Belgium|Canada|France|Germany|Hungary|Italy|Poland|Spain	1
United States|Argentina|Brazil|Canada|Finland	1
United States|Argentina|Peru|Puerto Rico	1
United States|Australia|Austria|Belgium|Canada|Denmark|Finland|France|Italy|Japan|Latvia|Netherlands|New Zealand|Poland|Singapore|Spain	1
United States|Australia|Austria|Belgium|Denmark|Finland|France|Germany|Japan|Latvia|Malaysia|Netherlands|New Zealand|Poland|Portugal|Singapore|United Kingdom	1
United States|Australia|Belgium|Canada|Czechia|Denmark|France|Hungary|Korea, Republic of|Lithuania|Netherlands|New Zealand|Norway|Serbia|Sweden|United Kingdom	1
United States|Australia|Belgium|Canada|Denmark|Germany|Hungary|Israel|Korea, Republic of|Netherlands|New Zealand|Spain|Switzerland	1
United States|Australia|Belgium|Canada|France|Italy|Netherlands|Poland|Spain	1
United States|Australia|Belgium|Canada|France|Italy|Netherlands|Spain	1
United States|Australia|Belgium|Denmark|France|Germany|Italy|Netherlands|New Zealand|Portugal|Spain|United Kingdom	1
United States|Australia|Belgium|Egypt|Finland|Germany|Italy|Japan|Korea, Republic of|Latvia|Netherlands|Portugal|Saudi Arabia|South Africa|Spain|Turkey|United Kingdom	1
United States|Australia|Belgium|France|Japan|Latvia|New Zealand	1
United States|Australia|Belgium|France|Japan|New Zealand	1
United States|Australia|Canada|China|New Zealand|Singapore|Taiwan	1
United States|Australia|Canada|Germany	1
United States|Australia|Canada|Singapore	1
United States|Australia|China|Italy|Japan|Korea, Republic of|New Zealand|Singapore|Taiwan	1
United States|Australia|Germany|New Zealand	1
United States|Australia|Malaysia|New Zealand	1
United States|Australia|New Zealand|Singapore	1
United States|Austria|Belgium|Canada|Germany|Switzerland	1
United States|Austria|Canada|China|Croatia|Germany|Italy|Japan|Korea, Republic of|Netherlands|Portugal|Serbia|Singapore	1
United States|Austria|Canada|Germany|Spain|United Kingdom	1
United States|Belarus|Bulgaria|Canada|Czech Republic|Georgia|Germany|Israel|Poland|Russian Federation|Serbia|Slovakia|Slovenia|Ukraine	1
United States|Belgium|Canada|Czechia|Denmark|France|Germany|Hungary|Italy|Netherlands|Serbia|Sweden|United Kingdom	1
United States|Belgium|Canada|Japan|Netherlands|Spain|Switzerland|United Kingdom	1
United States|Belgium|Canada|Netherlands|Poland|Spain	1
United States|Belgium|Denmark|Israel|Netherlands|South Africa|United Kingdom	1
United States|Belgium|France|Germany|Latvia|Netherlands|Spain	1
United States|Belgium|Germany|Italy|Japan|Netherlands|Spain|United Kingdom	1
United States|Belgium|Israel|Spain	1
United States|Brazil	1
United States|Brazil|Canada|Denmark|Germany|Japan|Netherlands|Singapore	1
United States|Brazil|Germany|Japan|Latvia|Sweden|Switzerland	1
United States|Brazil|India|Italy|Korea, Republic of|Poland	1
United States|Canada|China|Germany|India|Japan|Taiwan	1
United States|Canada|Czech Republic|Germany|Hungary|New Zealand|Norway|Slovakia|South Africa	1
United States|Canada|Czech Republic|Germany|South Africa|United Kingdom	1
United States|Canada|Denmark|Netherlands|Singapore|Sweden|United Kingdom	1
United States|Canada|Denmark|United Kingdom	1
United States|Canada|Finland|France|Germany|Netherlands	1
United States|Canada|Finland|Puerto Rico	1
United States|Canada|Germany|United Kingdom	1
United States|Canada|India	1
United States|Canada|Korea, Republic of|Mexico	1
United States|Colombia	1
United States|Colombia|Germany|Latvia|Netherlands	1
United States|Czechia|Netherlands|United Kingdom	1
United States|Denmark|Germany|Israel|Netherlands	1
United States|France|Germany|Israel	1
United States|France|Germany|Korea, Republic of|New Zealand|Switzerland|United Kingdom	1
United States|France|Germany|Netherlands	1
United States|France|Germany|United Kingdom	1
United States|Germany	1
United States|Germany|Ireland	1
United States|India	1
United States|Israel|Austria|Belgium|Canada|Czech Republic|France|Germany|Italy|Netherlands|Poland|Russian Federation|Spain|Sweden|United Kingdom	1
United States|Netherlands	1
United States|New Zealand|Singapore|Taiwan	1
United States|Puerto Rico	1
United States|Ukraine	1
Venezuela	1
Venezuela|United States|Argentina|Brazil|Chile|Colombia|Lithuania|Netherlands|Peru	1

Sites per Study

Site_count	Study_Count
1	1312
2	110
3	49
4	35
5	35
6	26
7	14
8	14
9	16
10	17
11	9
12	18
13	13
14	8
15	13
16	9
17	12
18	6
19	4
20	6
21	1
23	5
24	3
25	8
26	3
27	6
28	7
29	3
30	3
32	2
33	3
34	4
35	2
36	2
37	2
38	2
39	3
41	3
44	1
45	1
46	3
48	2
49	1
50	3
51	3
52	3
53	1
54	1
56	1
58	2
59	1
60	1
61	1
62	3
64	1
65	2
69	1
73	1
74	1
81	1
82	1
86	2
89	1
90	1
92	2
93	1
95	1
102	1
110	1
112	1
119	1
120	1
121	1
122	1
124	1
126	1
128	1
130	1
133	1
135	1
138	1
144	1
147	1
150	1
154	1
177	1
188	1
195	2
218	1
241	1
256	1
314	1
320	1
471	1
578	1
1091	1

Phase

Phase	Study_Count
N/A	891
Phase 4	417
Phase 3	227
Phase 2	173
Phase 1	67
Phase 2/Phase 3	47
Phase 1/Phase 2	30
Early Phase 1	10

Number of Arms

Number_of_Arms	Count_of_Studies
1	331
2	1067
3	170
4	67
5	6
6	15
8	2
11	1
NA	203

Number of Updates

Count of Versions	Count of Studies
1	162
2	289
3	272
4	237
5	182
6	162
7	128
8	82
9	70
10	47
11	25
12	36
13	22
14	25
15	13
16	19
17	11
18	9
19	6
20	5
21	7
22	6
23	4
24	2
25	1
26	4
27	1
28	2
29	4
30	1
32	4
34	1
35	1
36	2
37	1
38	1
40	1
44	1
45	1
54	1
56	1
57	2
60	2
67	1
71	1
73	1
77	1
79	1
80	1
88	1
97	1
98	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	9810	1700	5.770588
Contacts/Locations	4105	1409	2.913414
Recruitment Status	2546	1440	1.768056
Study Design	1867	1248	1.495994
None (earliest Version on record)	1862	1862	1.000000
Outcome Measures	1569	915	1.714754
Arms	1158	765	1.513726
Interventions	1158	765	1.513726
Sponsor/Collaborators	1147	764	1.501309
Study Description	986	627	1.572568
Eligibility	944	632	1.493671
Study Identification	940	633	1.484992
Oversight	637	540	1.179630
More Information	448	175	2.560000
References	419	291	1.439863
Conditions	357	297	1.202020
Results	295	295	1.000000
IPDSharing	195	180	1.083333
Baseline Characteristics	109	87	1.252874
Results Submission Events	94	94	1.000000
Reported Adverse Events	74	65	1.138462
Participant Flow	62	53	1.169811
Documents	58	49	1.183674
2020 Documents	1	1	1.000000
2020 Study Status	1	1	1.000000
Quality Control Review has not concludedReturned: April 13	1	1	1.000000
Quality Control Review has not concludedReturned: March 27	1	1	1.000000

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	20.00	1.0000	5.0000	10.0000	2.0000	18.0000	20.000	11.0000
1st Qu.	24.00	60.0000	15.5000	29.2500	35.0000	59.5000	100.000	62.0000
Median	39.00	137.0000	32.0000	56.5000	79.0000	120.0000	281.000	179.0000
Mean	45.20	573.4045	177.0299	115.5667	193.0643	292.9149	1244.472	870.4747
3rd Qu.	49.75	417.0000	64.0000	134.7500	150.0000	319.0000	769.250	634.5000
Max.	92.00	61301.0000	8400.0000	643.0000	10000.0000	3043.0000	25673.000	25682.0000

Trial Group Type

group_type	Group_Count
Experimental	1541
Active Comparator	1091
Placebo Comparator	292
Other	225
No Intervention	220
NA	203
Sham Comparator	21

Intervention Model

intervention_model	Study_Count
Parallel Assignment	1217
Single Group Assignment	450
Crossover Assignment	109
Factorial Assignment	45
NA	24
Sequential Assignment	17

Primary Purpose

primary_purpose	Study_Count
Treatment	1151
Diagnostic	235
Prevention	210
Basic Science	71
Supportive Care	51
Health Services Research	47
Other	42
NA	38
Screening	15
Device Feasibility	1
Educational/Counseling/Training	1

Observational Studies

Studies by Country

Country	Study_Count
United States	184
NA	124
Korea, Republic of	53
Germany	41
China	39
Canada	29
United Kingdom	28
France	18
Italy	18
Netherlands	17
Denmark	15
Switzerland	14
Japan	12
Brazil	11
Norway	11
Israel	10
Sweden	9
Finland	8
Poland	8
Austria	7
Greece	7
Singapore	7
Belgium	6
India	6
Russian Federation	6
Turkey	6
Egypt	4
Spain	4
United States|Canada	4
Croatia	3
Taiwan	3
Hong Kong	2
Iran, Islamic Republic of	2
Romania	2
United States|Denmark	2
Argentina|Belgium|Brazil|Denmark|Finland|France|Germany|Greece|Italy|Luxembourg|Mexico|Netherlands|Norway|Poland|Romania|Slovenia|Spain|Turkey|United Kingdom|Venezuela	1
Argentina|Norway	1
Australia	1
Austria|Bangladesh|Belarus|Brazil|Bulgaria|Chile|Czechia|Denmark|Egypt|Estonia|France|Georgia|Germany|Hungary|Indonesia|Ireland|Israel|Latvia|Lithuania|Malta|Mexico|Netherlands|Poland|Romania|Russian Federation|Serbia|Slovenia|Spain|Sweden|Taiwan|Ukraine|United Kingdom	1
Austria|Belgium|Bulgaria|Germany|Italy|Netherlands|Poland|Switzerland|United Kingdom	1
Austria|Belgium|Denmark|France|Germany|Hungary|Ireland|Italy|Netherlands|Spain|United Kingdom	1
Austria|Czechia|Denmark|France|Germany|Ireland|Jordan|Latvia|Lithuania|Morocco|Poland|Portugal|Russian Federation|Spain|Switzerland|United Kingdom	1
Austria|Germany	1
Bangladesh	1
Belgium|Bulgaria|Croatia|Czechia|Denmark|Finland|Germany|Greece|Hungary|Netherlands|Poland|Slovakia|Spain|Sweden|Switzerland|United Kingdom	1
Belgium|France	1
Belgium|France|Germany|Hungary|Ireland|Italy|Latvia|Poland|Spain|United Kingdom	1
Belgium|France|Germany|Italy|Switzerland	1
Belgium|Germany|Ireland|Italy|Switzerland	1
Belgium|Singapore	1
Belgium|Sweden|United Kingdom	1
Brazil|Germany|Italy|United Kingdom	1
Bulgaria	1
China|India|Korea, Republic of|Singapore	1
China|India|Malaysia|Sri Lanka|Vietnam	1
China|Korea, Republic of|Malaysia|Taiwan|Thailand	1
Denmark|France|Germany|Italy|Japan|Netherlands|United Kingdom	1
Denmark|Netherlands|New Zealand|Poland	1
Ecuador	1
Germany|Hungary	1
Germany|Italy|Portugal|Spain	1
Germany|Malaysia|Spain	1
Germany|Poland	1
Hungary	1
Pakistan	1
Paraguay	1
Portugal	1
Portugal|Spain	1
Qatar	1
Slovenia	1
Spain|Sweden	1
Spain|Switzerland|United Kingdom	1
Spain|United Kingdom	1
Trinidad and Tobago	1
United States|Austria|Belgium|Denmark|France|Germany|Italy|United Kingdom	1
United States|Austria|Canada|Egypt|Estonia|Germany|Greece|India|Italy|Japan|Netherlands|Portugal|Saudi Arabia|Spain|United Kingdom	1
United States|Austria|Canada|Germany|Italy|Korea, Republic of|Switzerland	1
United States|Belgium|Czech Republic|Netherlands|Sweden	1
United States|Belgium|Denmark|France|Germany|Italy|Netherlands|Poland|Spain|Sweden|Switzerland|United Kingdom	1
United States|Belgium|Denmark|Israel	1
United States|Belgium|France|Italy|Korea, Republic of|Netherlands|Portugal|Sweden|United Kingdom	1
United States|Belgium|France|Slovakia	1
United States|Bulgaria	1
United States|Canada|China|Italy|Japan|Korea, Republic of|Latvia|Netherlands	1
United States|Canada|Puerto Rico	1
United States|Canada|Switzerland	1
United States|Denmark|France|Italy|Latvia|Netherlands|Poland|United Kingdom	1
United States|France|Germany|Italy|Japan|Netherlands	1
United States|Germany|Japan|Netherlands|Spain|United Kingdom	1
United States|Italy|Latvia|Netherlands|Slovakia|United Kingdom	1
United States|Netherlands|United Kingdom	1
United States|Saudi Arabia	1

Sites per Study

Site_count	Study_Count
1	597
2	37
3	15
4	13
5	11
6	10
7	3
8	7
9	6
10	8
11	4
12	3
13	3
14	1
15	2
16	2
17	1
18	3
19	3
20	4
21	1
22	1
23	4
24	3
25	1
26	1
28	2
29	3
33	2
34	1
35	1
37	1
38	1
40	3
41	1
42	2
43	1
44	1
47	1
50	2
58	1
68	1
69	1
71	1
81	1
82	1
90	1
107	1
183	1
257	1
411	1

Number of Updates

Count of Versions	Count of Studies
1	122
2	133
3	159
4	95
5	71
6	46
7	29
8	21
9	28
10	10
11	9
12	9
13	8
14	5
15	5
16	4
17	2
18	3
19	3
21	1
22	2
23	1
24	2
26	1
28	1
29	1
31	1
32	1
36	1
63	1
106	1
124	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	3082	655	4.705343
Contacts/Locations	1033	481	2.147609
Recruitment Status	778	513	1.516569
None (earliest Version on record)	777	777	1.000000
Study Design	680	464	1.465517
Sponsor/Collaborators	386	288	1.340278
Study Description	345	220	1.568182
Eligibility	323	247	1.307692
Outcome Measures	319	241	1.323651
Study Identification	311	220	1.413636
Groups	184	138	1.333333
Interventions	184	138	1.333333
Oversight	163	151	1.079470
References	139	87	1.597701
Conditions	111	86	1.290698
IPDSharing	62	58	1.068966
More Information	41	20	2.050000
Results	36	36	1.000000
Results Submission Events	16	16	1.000000
Baseline Characteristics	14	11	1.272727
Reported Adverse Events	13	9	1.444444
Documents	9	9	1.000000
Participant Flow	9	7	1.285714

Enrollment Metrics

Measure	Observational
Min	1.000
1st Qu	96.000
Median	300.000
Mean	6401.925
3rd Qu	1111.500
Max	1758584.000

Observation Model

observational_model	Study_Count
Cohort	445
Case-Only	93
NA	86
Case-Control	44
Case Control	43
Other	43
Case-Crossover	7
Defined Population	4
Defined Population, Natural History	4
Ecologic or Community	4
Family-Based	2
Case Control, Natural History	1
Natural History	1

Time Perspective

time_perspective	Study_Count
Prospective	534
Retrospective	99
Cross-Sectional	68
NA	53
Other	12
Longitudinal, Prospective	6
Cross-Sectional, Prospective	2
Cross-Sectional, Retrospective	1
Longitudinal, Retrospective	1
Longitudinal, Retrospective/Prospective	1

Registries

Studies by Country

Country	Study_Count
China	18
Korea, Republic of	17
United States	15
Italy	13
Spain	9
Germany	8
Netherlands	7
Belgium	5
Japan	5
NA	5
Greece	4
Brazil	3
Russian Federation	3
France	2
Singapore	2
Switzerland	2
United Kingdom	2
Argentina|Armenia|Austria|Bangladesh|Belarus|Belgium|Brazil|Bulgaria|Chile|Colombia|Czechia|Egypt|Estonia|France|Georgia|Hungary|Iceland|India|Indonesia|Ireland|Israel|Japan|Jordan|Kazakhstan|Kuwait|Lebanon|Lithuania|Malaysia|Mexico|Morocco|Netherlands|North Macedonia|Oman|Poland|Portugal|Romania|Saudi Arabia|Serbia|Slovakia|South Africa|Spain|Sweden|Switzerland|Thailand|Tunisia|Ukraine|United Arab Emirates|United Kingdom|Uzbekistan|Vietnam	1
Australia|Germany|United Kingdom	1
Belgium|Canada|Germany|Japan|Singapore	1
Belgium|Hong Kong	1
Belgium|Netherlands	1
Canada	1
Denmark|Norway	1
Egypt	1
Finland	1
France|Germany|Italy|Spain	1
France|Germany|Switzerland	1
Germany|Austria|Ireland|Italy|Spain|Switzerland|Turkey|United Kingdom	1
Germany|Malaysia|Spain	1
India	1
Indonesia	1
Israel	1
Mexico	1
Netherlands|Poland|Spain|United Kingdom	1
Netherlands|Russian Federation	1
Norway	1
Poland	1
Portugal	1
Portugal|Spain	1
Sweden	1
Thailand	1
Tunisia	1
Turkey	1
United States|Argentina|Canada|India|Italy	1
United States|Canada|Egypt|Greece|Lebanon|Russian Federation	1
United States|Canada|Germany|Israel	1
United States|India|Singapore	1
United States|Israel	1

Sites per Study

Site_count	Study_Count
1	92
2	6
3	5
4	8
5	2
6	3
7	5
8	1
9	2
11	2
13	1
14	2
15	1
16	3
17	1
18	1
19	1
20	1
21	1
22	1
24	1
26	2
31	1
36	2
37	2
44	1
48	1
52	1
54	1
462	1

Number of Updates

Count of Versions	Count of Studies
1	22
2	33
3	29
4	17
5	15
6	12
7	5
8	3
9	5
10	1
11	3
12	2
13	1
15	1
18	2
50	1

Update History Change Type

Change Type	Count_of_Changes	Count_of_Studies	ratio
Study Status	520	130	4.000000
Contacts/Locations	282	99	2.848485
None (earliest Version on record)	152	152	1.000000
Recruitment Status	143	95	1.505263
Study Design	100	71	1.408451
Study Description	55	40	1.375000
Outcome Measures	50	41	1.219512
Oversight	40	37	1.081081
Study Identification	35	32	1.093750
Eligibility	31	26	1.192308
Sponsor/Collaborators	25	22	1.136364
References	23	12	1.916667
Groups	22	20	1.100000
Interventions	22	20	1.100000
Conditions	15	14	1.071429
IPDSharing	14	13	1.076923
Results	4	4	1.000000
Documents	3	2	1.500000
Results Submission Events	3	3	1.000000
Baseline Characteristics	1	1	1.000000
More Information	1	1	1.000000

Enrollment Metrics

Measure	Registries
Min	28.00
1st Qu	300.00
Median	1000.00
Mean	91393.95
3rd Qu	2350.00
Max	7205000.00

Registry Model

observational_model	Study_Count
Cohort	108
Case-Only	23
Other	14
Case-Control	6
Case-Crossover	1

Time Perspective

time_perspective	Study_Count
Prospective	138
Other	6
Cross-Sectional	5
NA	2
Retrospective	1

Follow-up

target_duration	Study_Count
5 Years	33
12 Months	24
1 Year	18
3 Years	13
2 Years	12
1 Day	11
10 Years	6
24 Months	6
1 Month	4
6 Months	4
18 Months	3
3 Days	3
9 Months	3
1 Week	2
3 Months	2
1095 Days	1
12 Weeks	1
17 Years	1
2 Days	1
30 Days	1
36 Months	1
7 Days	1
90 Days	1